VPS37D report

I. Expression across cell types

Insufficient scRNA-seq data for expression of VPS37D at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of VPS37D at tissue level.

III. Associated gene sets

GO_0006623Biological processprotein targeting to vacuole
GO_0016236Biological processmacroautophagy
GO_0039702Biological processviral budding via host ESCRT complex
GO_0036258Biological processmultivesicular body assembly
GO_0006612Biological processprotein targeting to membrane
GO_0043162Biological processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0043328Biological processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0090148Biological processmembrane fission
GO_0010008Cellular componentendosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0031902Cellular componentlate endosome membrane
GO_0000813Cellular componentESCRT I complex
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameVPS37D
Protein nameVPS37D subunit of ESCRT-I
Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome chromosomal region 24 protein)
SynonymsWBSCR24
DescriptionFUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. .

AccessionsENST00000324941.5
C9JYT9
ENST00000451519.1
Q86XT2