I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 9 studies | 27% ± 7% | |
| neutrophil | 7 studies | 37% ± 15% | |
| germinal center B cell | 3 studies | 26% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 9 studies | 27% ± 7% | |
| neutrophil | 7 studies | 37% ± 15% | |
| germinal center B cell | 3 studies | 26% ± 7% |
Insufficient scRNA-seq data for expression of VNN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 2422.95 | 577 / 578 | 76% | 6.73 | 880 / 1155 |
| kidney | 72% | 244.60 | 64 / 89 | 75% | 9.33 | 680 / 901 |
| liver | 76% | 283.68 | 171 / 226 | 70% | 17.43 | 285 / 406 |
| pancreas | 24% | 60.78 | 79 / 328 | 87% | 16.38 | 154 / 178 |
| prostate | 43% | 133.27 | 106 / 245 | 59% | 4.32 | 295 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 59.34 | 29 / 29 |
| peripheral blood | 100% | 65116.74 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6963.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| intestine | 49% | 210.61 | 478 / 966 | 48% | 4.65 | 254 / 527 |
| stomach | 40% | 173.80 | 145 / 359 | 57% | 5.56 | 163 / 286 |
| bladder | 57% | 181.38 | 12 / 21 | 36% | 2.72 | 179 / 504 |
| breast | 44% | 131.80 | 200 / 459 | 41% | 2.33 | 453 / 1118 |
| adipose | 80% | 548.16 | 958 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 5.13 | 32 / 45 |
| esophagus | 22% | 62.45 | 315 / 1445 | 44% | 4.76 | 80 / 183 |
| uterus | 23% | 72.15 | 39 / 170 | 41% | 5.68 | 186 / 459 |
| thymus | 35% | 110.63 | 231 / 653 | 27% | 2.10 | 166 / 605 |
| adrenal gland | 43% | 93.53 | 110 / 258 | 17% | 1.13 | 40 / 230 |
| ovary | 18% | 46.21 | 32 / 180 | 40% | 1.82 | 170 / 430 |
| heart | 49% | 138.99 | 422 / 861 | 0% | 0 | 0 / 0 |
| skin | 2% | 6.34 | 43 / 1809 | 45% | 3.09 | 212 / 472 |
| brain | 12% | 25.95 | 328 / 2642 | 31% | 1.99 | 218 / 705 |
| blood vessel | 43% | 176.26 | 578 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 15% | 0.63 | 12 / 80 |
| muscle | 8% | 15.29 | 66 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015939 | Biological process | pantothenate metabolic process |
| GO_0098552 | Cellular component | side of membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0017159 | Molecular function | pantetheine hydrolase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | VNN2 |
| Protein name | Vanin 2 (cDNA FLJ55137, highly similar to Vascular non-inflammatory molecule 2) Vanin 2 Pantetheine hydrolase VNN2 (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4) (Vascular non-inflammatory molecule 2) (Vanin-2) |
| Synonyms | |
| Description | FUNCTION: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine . Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil. . |
| Accessions | O95498 B4DQB2 ENST00000531279.5 ENST00000524919.5 E9PL76 ENST00000528801.5 ENST00000525674.5 [O95498-4] ENST00000525270.5 [O95498-6] ENST00000392389.6 ENST00000533835.5 ENST00000422400.6 ENST00000525289.5 [O95498-2] ENST00000326499.11 [O95498-1] E9PRD9 ENST00000418593.6 E9PQ75 ENST00000530536.5 ENST00000532053.5 [O95498-3] ENST00000532012.1 J3KQ55 E9PLK5 E9PK31 J3KQQ7 J3QT03 |
