VARS2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of VARS2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of VARS2 at tissue level.

III. Associated gene sets

GO_0106074Biological processaminoacyl-tRNA metabolism involved in translational fidelity
GO_0006438Biological processvalyl-tRNA aminoacylation
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0002161Molecular functionaminoacyl-tRNA editing activity
GO_0004832Molecular functionvaline-tRNA ligase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameVARS2
Protein nameValine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) (Valyl-tRNA synthetase-like)
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase)
Valine--tRNA ligase, mitochondrial (Valyl-tRNA synthetase 2, mitochondrial)
SynonymsVARSL
VARS2L
KIAA1885
DescriptionFUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

FUNCTION: Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val). .

AccessionsA2ABL6
ENST00000548165.2
ENST00000431578.5
ENST00000428017.5
ENST00000452966.5
B7ZL25
ENST00000676266.1 [Q5ST30-1]
ENST00000551709.2
ENST00000428577.6
ENST00000549458.5
ENST00000425563.5
ENST00000552560.5
Q5ST30
A0A140TA36
ENST00000414570.5
ENST00000433908.5
A0A0G2JL52
A0A140T8Y0
ENST00000553245.5
ENST00000625423.2 [Q5ST30-3]
A0A0G2JIA5
ENST00000421263.1
B4E0K6
ENST00000415079.6 [Q5ST30-1]
ENST00000549900.2
B7ZCJ6
ENST00000547340.2
ENST00000383369.7
ENST00000416187.5
ENST00000450090.6
ENST00000434089.5
A0A140TA40
ENST00000541562.6 [Q5ST30-1]
ENST00000383540.7
A0A0A0MTG1
ENST00000550773.2
ENST00000548842.5
ENST00000443384.5
ENST00000411697.5
A0A140TA45
ENST00000672801.1
A0A140TA35
ENST00000546854.5 [Q5ST30-4]
ENST00000446577.5
ENST00000321897.9 [Q5ST30-1]