I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 23% ± 8% | |
| dendritic cell | 3 studies | 30% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 23% ± 8% | |
| dendritic cell | 3 studies | 30% ± 3% |
Insufficient scRNA-seq data for expression of VARS1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4656.07 | 1445 / 1445 | 100% | 84.39 | 183 / 183 |
| ovary | 100% | 3893.20 | 180 / 180 | 100% | 60.53 | 430 / 430 |
| pancreas | 100% | 4044.72 | 328 / 328 | 100% | 56.00 | 178 / 178 |
| skin | 100% | 6663.09 | 1809 / 1809 | 100% | 141.17 | 471 / 472 |
| stomach | 100% | 3699.04 | 359 / 359 | 100% | 82.86 | 285 / 286 |
| intestine | 100% | 4079.75 | 966 / 966 | 100% | 88.98 | 525 / 527 |
| uterus | 100% | 5398.98 | 170 / 170 | 99% | 67.92 | 456 / 459 |
| bladder | 100% | 4811.43 | 21 / 21 | 99% | 78.95 | 500 / 504 |
| breast | 100% | 4627.72 | 459 / 459 | 99% | 62.82 | 1108 / 1118 |
| thymus | 100% | 4005.19 | 652 / 653 | 99% | 44.43 | 600 / 605 |
| liver | 100% | 3383.02 | 226 / 226 | 99% | 57.75 | 402 / 406 |
| prostate | 100% | 3873.68 | 245 / 245 | 99% | 54.45 | 497 / 502 |
| lung | 99% | 4158.89 | 575 / 578 | 99% | 72.39 | 1148 / 1155 |
| kidney | 100% | 3621.76 | 89 / 89 | 97% | 40.82 | 872 / 901 |
| adrenal gland | 100% | 4754.44 | 258 / 258 | 96% | 47.73 | 221 / 230 |
| brain | 96% | 2467.06 | 2533 / 2642 | 100% | 65.44 | 704 / 705 |
| adipose | 100% | 4437.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 114.49 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 89.93 | 29 / 29 |
| muscle | 100% | 6774.05 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6037.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 71.70 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 83.55 | 1 / 1 |
| blood vessel | 100% | 3860.56 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 95% | 2503.91 | 818 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 2758.59 | 754 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0106074 | Biological process | aminoacyl-tRNA metabolism involved in translational fidelity |
| GO_0006438 | Biological process | valyl-tRNA aminoacylation |
| GO_0006418 | Biological process | tRNA aminoacylation for protein translation |
| GO_0005829 | Cellular component | cytosol |
| GO_0002161 | Molecular function | aminoacyl-tRNA editing activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004832 | Molecular function | valine-tRNA ligase activity |
| Gene name | VARS1 |
| Protein name | Valine--tRNA ligase (Valyl-tRNA synthetase 1) valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) Valine--tRNA ligase |
| Synonyms | VARS2 VARS G7A |
| Description | FUNCTION: Catalyzes the attachment of valine to tRNA(Val). . |
| Accessions | ENST00000425144.5 H0Y426 ENST00000455956.1 A0A140T954 ENST00000422694.6 A0A140T904 ENST00000457796.6 [P26640-1] ENST00000446350.1 ENST00000435299.1 ENST00000424984.1 A0A140T936 ENST00000375663.8 [P26640-1] ENST00000440048.1 ENST00000419375.1 ENST00000417430.1 ENST00000428505.1 ENST00000435657.6 ENST00000445152.1 ENST00000211402.10 [P26640-1] ENST00000424974.1 ENST00000428796.1 A2ABF4 ENST00000425864.1 ENST00000428445.1 ENST00000420919.1 A0A0G2JJT9 P26640 |
