UTP6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000462Biological processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0034388Cellular componentPwp2p-containing subcomplex of 90S preribosome
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0032040Cellular componentsmall-subunit processome
GO_0030515Molecular functionsnoRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUTP6
Protein nameUTP6 small subunit processome component
U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein)
SynonymsMHAT
HCA66
C17orf40
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. .

AccessionsQ9NYH9
ENST00000261708.9
ENST00000581012.6
J3KRR8
ENST00000579459.1
J3QSA7