UTP18 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042274Biological processribosomal small subunit biogenesis
GO_0006364Biological processrRNA processing
GO_0005730Cellular componentnucleolus
GO_0034388Cellular componentPwp2p-containing subcomplex of 90S preribosome
GO_0005654Cellular componentnucleoplasm
GO_0031965Cellular componentnuclear membrane
GO_0032040Cellular componentsmall-subunit processome
GO_0005634Cellular componentnucleus
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUTP18
Protein nameU3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50)
UTP18 small subunit processome component
SynonymsCGI-48
WDR50
CDABP0061
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. .

AccessionsENST00000583725.5
ENST00000508506.3
J3QRG0
ENST00000579261.6
ENST00000225298.12
ENST00000583205.5
J3QLD6
ENST00000582832.1
F6VJE8
Q9Y5J1
J3QR85
J3KSR7