USH1G | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of USH1G at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	68%	168.49	116 / 170	56%	3.42	256 / 459
adrenal gland	95%	153.84	244 / 258	26%	2.31	59 / 230
esophagus	39%	445.27	560 / 1445	52%	4.97	96 / 183
ovary	66%	66.09	118 / 180	20%	0.54	84 / 430
skin	70%	265.72	1263 / 1809	8%	0.28	36 / 472
tonsil	0%	0	0 / 0	73%	4.83	33 / 45
bladder	33%	31.76	7 / 21	25%	1.25	127 / 504
lung	0%	0	0 / 578	38%	3.04	443 / 1155
kidney	4%	2.22	4 / 89	20%	0.76	183 / 901
brain	16%	20.62	428 / 2642	1%	0.03	10 / 705
intestine	6%	7.46	61 / 966	5%	0.18	24 / 527
prostate	10%	6.27	24 / 245	0%	0.00	1 / 502
thymus	0%	0	0 / 653	9%	0.38	53 / 605
breast	0%	0	0 / 459	7%	0.17	78 / 1118
pancreas	0%	0	0 / 328	6%	0.22	10 / 178
stomach	1%	0.96	2 / 359	5%	0.12	14 / 286
liver	0%	0	0 / 226	3%	0.08	13 / 406
heart	3%	1.37	24 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.04	2 / 80
adipose	0%	0.50	6 / 1204	0%	0	0 / 0
muscle	0%	0.16	2 / 803	0%	0	0 / 0
blood vessel	0%	0.04	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007605	Biological process	sensory perception of sound
GO_0045494	Biological process	photoreceptor cell maintenance
GO_0050957	Biological process	equilibrioception
GO_0060122	Biological process	inner ear receptor cell stereocilium organization
GO_2000369	Biological process	regulation of clathrin-dependent endocytosis
GO_0050953	Biological process	sensory perception of light stimulus
GO_0042472	Biological process	inner ear morphogenesis
GO_0032391	Cellular component	photoreceptor connecting cilium
GO_0005886	Cellular component	plasma membrane
GO_0016607	Cellular component	nuclear speck
GO_0005813	Cellular component	centrosome
GO_0001917	Cellular component	photoreceptor inner segment
GO_0015629	Cellular component	actin cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0097546	Cellular component	ciliary base
GO_0015030	Cellular component	Cajal body
GO_0036064	Cellular component	ciliary basal body
GO_0097733	Cellular component	photoreceptor cell cilium
GO_0030507	Molecular function	spectrin binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	USH1G
Protein name	pre-mRNA splicing regulator USH1G (Scaffold protein containing ankyrin repeats and SAM domain) (Usher syndrome type-1G protein) Usher syndrome type 1G protein isoform 2 USH1 protein network component sans
Synonyms	SANS
Description	FUNCTION: Plays a role in pre-mRNA splicing by regulating the release and transfer of U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complexes from their assembly site in Cajal bodies to nuclear speckles, thereby contributing to the assembly of the pre-catalytic spliceosome on target pre-mRNAs . May also participate in recycling of snRNPs back to Cajal bodies during splicing . Plays a role in regulating MAGI2-mediated endocytosis . Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles. Required for normal hearing. .
Accessions	ENST00000614341.5 A0A385DPC5 Q495M9 J3KSN5 ENST00000579243.1

USH1G report