UQCC5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034551Biological processmitochondrial respiratory chain complex III assembly
GO_0033617Biological processmitochondrial cytochrome c oxidase assembly
GO_0005743Cellular componentmitochondrial inner membrane
GO_0097177Molecular functionmitochondrial ribosome binding

IV. Literature review

[source]
Gene nameUQCC5
Protein nameUbiquinol-cytochrome c reductase complex assembly factor 5
Ubiquinol-cytochrome c reductase complex assembly factor 5 (Small integral membrane protein 4)
SynonymsSMIM4
C3orf78
DescriptionFUNCTION: Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (By similarity). Mediates early complex III biogenesis (By similarity). Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also involved in the first steps of cytochrome c oxidase complex (complex IV) assembly . .

AccessionsC9JAX8
ENST00000476842.1
ENST00000307106.3
ENST00000477703.6
Q8WVI0
F8W7Q2