UPP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009116Biological processnucleoside metabolic process
GO_0006218Biological processuridine catabolic process
GO_0044206Biological processUMP salvage
GO_0046108Biological processuridine metabolic process
GO_0006249Biological processdCMP catabolic process
GO_0045098Cellular componenttype III intermediate filament
GO_0005829Cellular componentcytosol
GO_0004850Molecular functionuridine phosphorylase activity
GO_0047847Molecular functiondeoxyuridine phosphorylase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUPP2
Protein nameUridine phosphorylase (EC 2.4.2.3)
Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3)
Uridine phosphorylase 2 isoform 3
Uridine phosphorylase 2 isoform 4
Synonyms
DescriptionFUNCTION: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis . Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds . .

FUNCTION: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds. .

FUNCTION: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds. .

AccessionsA0A0S2Z698
ENST00000005756.5 [O95045-1]
A0A0S2Z639
A0A0S2Z6U5
O95045
ENST00000605860.5 [O95045-2]
A0A0S2Z634