UPK3A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of UPK3A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UPK3A at tissue level.

III. Associated gene sets

GO_0055078Biological processsodium ion homeostasis
GO_0015840Biological processurea transport
GO_0006833Biological processwater transport
GO_0000902Biological processcell morphogenesis
GO_0001822Biological processkidney development
GO_0055075Biological processpotassium ion homeostasis
GO_0030855Biological processepithelial cell differentiation
GO_0060157Biological processurinary bladder development
GO_0070062Cellular componentextracellular exosome
GO_0120001Cellular componentapical plasma membrane urothelial plaque
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUPK3A
Protein nameUroplakin-3a (UP3a) (Uroplakin III) (UPIII)
SynonymsUPK3
DescriptionFUNCTION: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). .

AccessionsENST00000396082.2 [O75631-2]
ENST00000216211.9 [O75631-1]
O75631