UNCX report

I. Expression across cell types

Insufficient scRNA-seq data for expression of UNCX at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UNCX at tissue level.

III. Associated gene sets

GO_0021516Biological processdorsal spinal cord development
GO_0021889Biological processolfactory bulb interneuron differentiation
GO_0010468Biological processregulation of gene expression
GO_0035726Biological processcommon myeloid progenitor cell proliferation
GO_0001502Biological processcartilage condensation
GO_0045595Biological processregulation of cell differentiation
GO_0007389Biological processpattern specification process
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameUNCX
Protein nameTruncated UNCX homeobox protein transcript variant 3
UNC homeobox protein transcript variant 1
Homeobox protein unc-4 homolog (Homeobox protein Uncx4.1)
Truncated UNCX homeobox protein transcript variant 2
SynonymsUNCX4.1
DescriptionFUNCTION: Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity). .

AccessionsA0A0A7EP36
A0A0A7EP75
A6NJT0
ENST00000316333.9
A0A0A7EPG2