Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 13 studies | 26% ± 13% | |
GABAergic neuron | 11 studies | 40% ± 22% | |
microglial cell | 10 studies | 30% ± 9% | |
glutamatergic neuron | 6 studies | 35% ± 18% | |
non-classical monocyte | 6 studies | 25% ± 12% | |
interneuron | 6 studies | 42% ± 15% | |
gamma-delta T cell | 5 studies | 21% ± 3% | |
oligodendrocyte precursor cell | 5 studies | 24% ± 6% | |
natural killer cell | 5 studies | 22% ± 4% | |
T cell | 5 studies | 22% ± 5% | |
myeloid cell | 5 studies | 28% ± 10% | |
monocyte | 5 studies | 30% ± 10% | |
dendritic cell | 4 studies | 19% ± 3% | |
lymphocyte | 4 studies | 25% ± 9% | |
alveolar macrophage | 4 studies | 35% ± 12% | |
GABAergic interneuron | 3 studies | 44% ± 4% | |
granule cell | 3 studies | 44% ± 18% | |
neuron | 3 studies | 24% ± 3% | |
pericyte | 3 studies | 31% ± 21% | |
CD4-positive, alpha-beta T cell | 3 studies | 19% ± 2% | |
Schwann cell | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 6 studies | 35% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 98% | 1524.43 | 1774 / 1809 | 84% | 7.24 | 398 / 472 |
lung | 100% | 1268.86 | 577 / 578 | 82% | 5.71 | 947 / 1155 |
brain | 87% | 1635.64 | 2294 / 2642 | 77% | 4.31 | 541 / 705 |
bladder | 76% | 420.05 | 16 / 21 | 77% | 7.18 | 387 / 504 |
esophagus | 49% | 186.53 | 703 / 1445 | 88% | 6.31 | 161 / 183 |
thymus | 83% | 433.00 | 543 / 653 | 53% | 4.51 | 320 / 605 |
intestine | 82% | 350.88 | 788 / 966 | 52% | 2.94 | 274 / 527 |
breast | 77% | 306.41 | 353 / 459 | 51% | 2.88 | 574 / 1118 |
kidney | 55% | 229.06 | 49 / 89 | 67% | 3.87 | 608 / 901 |
stomach | 57% | 181.19 | 205 / 359 | 63% | 3.28 | 180 / 286 |
pancreas | 25% | 72.95 | 83 / 328 | 89% | 7.61 | 159 / 178 |
uterus | 36% | 98.21 | 62 / 170 | 73% | 5.49 | 333 / 459 |
spleen | 100% | 4022.02 | 241 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 68% | 190.22 | 176 / 258 | 30% | 1.42 | 68 / 230 |
peripheral blood | 92% | 926.11 | 857 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 4.96 | 24 / 29 |
prostate | 67% | 226.55 | 164 / 245 | 14% | 0.45 | 72 / 502 |
tonsil | 0% | 0 | 0 / 0 | 80% | 3.65 | 36 / 45 |
adipose | 77% | 428.45 | 932 / 1204 | 0% | 0 | 0 / 0 |
ovary | 11% | 23.83 | 19 / 180 | 61% | 2.98 | 261 / 430 |
blood vessel | 51% | 198.58 | 675 / 1335 | 0% | 0 | 0 / 0 |
liver | 19% | 60.00 | 44 / 226 | 21% | 2.81 | 85 / 406 |
muscle | 34% | 193.36 | 276 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 26% | 0.78 | 21 / 80 |
heart | 25% | 105.63 | 214 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051279 | Biological process | regulation of release of sequestered calcium ion into cytosol |
GO_0038063 | Biological process | collagen-activated tyrosine kinase receptor signaling pathway |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0035335 | Biological process | peptidyl-tyrosine dephosphorylation |
GO_0090331 | Biological process | negative regulation of platelet aggregation |
GO_0070527 | Biological process | platelet aggregation |
GO_0045779 | Biological process | negative regulation of bone resorption |
GO_0009968 | Biological process | negative regulation of signal transduction |
GO_0045670 | Biological process | regulation of osteoclast differentiation |
GO_0045671 | Biological process | negative regulation of osteoclast differentiation |
GO_0005634 | Cellular component | nucleus |
GO_0005737 | Cellular component | cytoplasm |
GO_0051219 | Molecular function | phosphoprotein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | UBASH3B |
Protein name | Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2) |
Synonyms | STS1 KIAA1959 |
Description | FUNCTION: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. . |
Accessions | Q8TF42 ENST00000284273.6 |