Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 30% ± 14% | |
| endothelial cell | 4 studies | 23% ± 3% | |
| fibroblast | 3 studies | 24% ± 6% | |
| ciliated cell | 3 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 31% ± 7% | |
| glutamatergic neuron | 3 studies | 45% ± 5% | |
| dendritic cell | 3 studies | 33% ± 9% | |
| basal cell | 3 studies | 22% ± 2% | |
| astrocyte | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1728.51 | 1445 / 1445 | 100% | 16.26 | 183 / 183 |
| prostate | 100% | 1723.26 | 245 / 245 | 100% | 20.29 | 502 / 502 |
| breast | 100% | 1545.09 | 459 / 459 | 100% | 18.89 | 1116 / 1118 |
| thymus | 100% | 1660.56 | 653 / 653 | 100% | 19.19 | 602 / 605 |
| uterus | 100% | 1964.32 | 170 / 170 | 99% | 15.07 | 456 / 459 |
| brain | 100% | 1151.90 | 2636 / 2642 | 99% | 11.31 | 701 / 705 |
| lung | 99% | 1189.80 | 575 / 578 | 100% | 13.61 | 1151 / 1155 |
| bladder | 100% | 2059.90 | 21 / 21 | 99% | 12.03 | 499 / 504 |
| kidney | 100% | 1384.09 | 89 / 89 | 99% | 14.48 | 891 / 901 |
| ovary | 100% | 1995.09 | 180 / 180 | 99% | 13.37 | 424 / 430 |
| stomach | 100% | 1316.57 | 359 / 359 | 99% | 13.24 | 282 / 286 |
| pancreas | 100% | 807.70 | 327 / 328 | 99% | 11.89 | 176 / 178 |
| intestine | 100% | 1683.65 | 965 / 966 | 98% | 12.82 | 519 / 527 |
| liver | 100% | 738.32 | 226 / 226 | 97% | 8.68 | 393 / 406 |
| skin | 100% | 1334.48 | 1804 / 1809 | 97% | 18.92 | 457 / 472 |
| adrenal gland | 100% | 1725.43 | 258 / 258 | 96% | 11.53 | 221 / 230 |
| blood vessel | 100% | 1941.70 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.25 | 29 / 29 |
| spleen | 100% | 1315.62 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.33 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.52 | 1 / 1 |
| adipose | 100% | 1480.61 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 98% | 643.29 | 789 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 1183.46 | 845 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 12.05 | 75 / 80 |
| peripheral blood | 34% | 925.67 | 315 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031591 | Biological process | wybutosine biosynthetic process |
| GO_0030488 | Biological process | tRNA methylation |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0008175 | Molecular function | tRNA methyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TYW3 |
| Protein name | tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) TYW3 protein tRNA wybutosine-synthesizing protein 3 homolog (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase) |
| Synonyms | C1orf171 |
| Description | FUNCTION: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). . FUNCTION: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. . FUNCTION: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. . |
| Accessions | ENST00000479111.5 ENST00000483990.1 Q6IPR3 V9GZ67 V9GY40 ENST00000370867.8 [Q6IPR3-1] ENST00000457880.6 [Q6IPR3-2] Q96GE7 |