TUBA8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TUBA8 at tissue level.

III. Associated gene sets

GO_0000278Biological processmitotic cell cycle
GO_0007286Biological processspermatid development
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0001669Cellular componentacrosomal vesicle
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005874Cellular componentmicrotubule
GO_0005737Cellular componentcytoplasm
GO_0005525Molecular functionGTP binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0016787Molecular functionhydrolase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameTUBA8
Protein nameTubulin alpha chain
Tubulin alpha 8
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
SynonymsTUBAL2
DescriptionFUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. .

FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. .

FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. .

AccessionsENST00000679963.1
Q9NY65
A0A7P0T945
ENST00000416740.2 [Q9NY65-2]
ENST00000316027.10 [Q9NY65-2]
ENST00000680175.1
C9K0S6
V9GZ17
ENST00000608634.1
ENST00000416740
C9J2C0
A0A7P0TA31
ENST00000330423.8 [Q9NY65-1]
ENST00000426208.5