TUB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0061512Biological processprotein localization to cilium
GO_0007605Biological processsensory perception of sound
GO_0050766Biological processpositive regulation of phagocytosis
GO_1903546Biological processprotein localization to photoreceptor outer segment
GO_0045494Biological processphotoreceptor cell maintenance
GO_0060041Biological processretina development in camera-type eye
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0097500Biological processreceptor localization to non-motile cilium
GO_0006910Biological processphagocytosis, recognition
GO_0042073Biological processintraciliary transport
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0120160Molecular functionintraciliary transport particle A binding
GO_0044877Molecular functionprotein-containing complex binding
GO_0001664Molecular functionG protein-coupled receptor binding

IV. Literature review

[source]
Gene nameTUB
Protein nameTubby-like protein
Tubby homologue
Tubby protein homolog
Synonyms
DescriptionFUNCTION: Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. .

AccessionsP50607
ENST00000305253.8 [P50607-2]
Q9H4D2
E9PQR4
Q96JS0
ENST00000534099.5
ENST00000299506.3 [P50607-1]