TTPA report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TTPA at tissue level.

III. Associated gene sets

GO_0120009Biological processintermembrane lipid transfer
GO_0051180Biological processvitamin transport
GO_0009636Biological processresponse to toxic substance
GO_0090212Biological processnegative regulation of establishment of blood-brain barrier
GO_0006629Biological processlipid metabolic process
GO_1900223Biological processpositive regulation of amyloid-beta clearance
GO_0042360Biological processvitamin E metabolic process
GO_0001892Biological processembryonic placenta development
GO_0005829Cellular componentcytosol
GO_0005770Cellular componentlate endosome
GO_1902936Molecular functionphosphatidylinositol bisphosphate binding
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0005515Molecular functionprotein binding
GO_0120013Molecular functionlipid transfer activity
GO_0008431Molecular functionvitamin E binding
GO_0043325Molecular functionphosphatidylinositol-3,4-bisphosphate binding

IV. Literature review

[source]
Gene nameTTPA
Protein nameAlpha-tocopherol transfer protein (Alpha-TTP)
SynonymsTPP1
DescriptionFUNCTION: Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells . Binds both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity). .

AccessionsP49638
ENST00000260116.5