TRPV6 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPV6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	95%	5734.91	232 / 245	100%	51.67	502 / 502
pancreas	100%	6064.38	328 / 328	79%	8.96	141 / 178
breast	56%	422.78	257 / 459	58%	4.03	647 / 1118
kidney	100%	998.47	89 / 89	5%	0.22	43 / 901
ureter	0%	0	0 / 0	100%	7.05	1 / 1
thymus	67%	157.46	435 / 653	31%	0.92	190 / 605
stomach	74%	682.74	265 / 359	16%	0.57	46 / 286
brain	62%	249.00	1636 / 2642	16%	0.35	110 / 705
skin	72%	959.25	1302 / 1809	2%	0.11	10 / 472
bladder	19%	46.76	4 / 21	44%	2.90	221 / 504
esophagus	37%	209.45	529 / 1445	23%	0.87	43 / 183
liver	45%	113.05	102 / 226	15%	1.03	59 / 406
ovary	5%	9.53	9 / 180	51%	1.13	219 / 430
uterus	7%	14.62	12 / 170	47%	2.42	217 / 459
tonsil	0%	0	0 / 0	42%	1.29	19 / 45
lung	11%	19.36	64 / 578	19%	0.51	225 / 1155
intestine	2%	5.34	15 / 966	14%	0.64	73 / 527
lymph node	0%	0	0 / 0	3%	0.06	1 / 29
peripheral blood	3%	5.09	26 / 929	0%	0	0 / 0
heart	2%	2.73	16 / 861	0%	0	0 / 0
spleen	2%	4.49	4 / 241	0%	0	0 / 0
adipose	2%	6.57	19 / 1204	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	1%	0.02	2 / 230
blood vessel	1%	1.92	7 / 1335	0%	0	0 / 0
muscle	0%	0.68	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0055074	Biological process	calcium ion homeostasis
GO_0098703	Biological process	calcium ion import across plasma membrane
GO_0017158	Biological process	regulation of calcium ion-dependent exocytosis
GO_0051592	Biological process	response to calcium ion
GO_0006816	Biological process	calcium ion transport
GO_0035898	Biological process	parathyroid hormone secretion
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0034704	Cellular component	calcium channel complex
GO_0005886	Cellular component	plasma membrane
GO_0005516	Molecular function	calmodulin binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity
GO_0046872	Molecular function	metal ion binding

Gene name	TRPV6
Protein name	ABP/ZF (TRPV6 protein) (Transient receptor potential cation channel, subfamily V, member 6, isoform CRA_a) Transient receptor potential cation channel subfamily V member 6 Transient receptor potential cation channel subfamily V member 6 (TrpV6) (CaT-like) (CaT-L) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2)
Synonyms	ECAC2 ZFAB hCG_19640
Description	FUNCTION: Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine . Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification . Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. .
Accessions	ENST00000633318.1 ENST00000359396 ENST00000431833.1 ENST00000436401.1 Q9H1D0 A0A0J9YXP5 C9JHY1 A0A0J9YW11 ENST00000359396.9 [Q9H1D0-1] Q9Y260 ENST00000633826.1 C9J9W0 V5NAT2 A0A0G2JMR5 A0A1X7SBT1 ENST00000611485.2

TRPV6 report