TRPV5 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPV5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	94%	533.46	84 / 89	1%	0.05	12 / 901
brain	89%	44.05	2358 / 2642	1%	0.01	5 / 705
pancreas	86%	13.41	281 / 328	0%	0	0 / 178
spleen	73%	9.78	177 / 241	0%	0	0 / 0
peripheral blood	60%	19.74	556 / 929	0%	0	0 / 0
breast	52%	11.27	238 / 459	2%	0.03	21 / 1118
prostate	53%	7.83	131 / 245	0%	0	0 / 502
thymus	44%	3.83	285 / 653	0%	0.00	1 / 605
uterus	44%	4.88	74 / 170	0%	0.00	1 / 459
lung	40%	3.68	232 / 578	0%	0.00	4 / 1155
esophagus	36%	3.30	516 / 1445	1%	0.01	2 / 183
muscle	28%	2.57	227 / 803	0%	0	0 / 0
adipose	26%	2.05	311 / 1204	0%	0	0 / 0
heart	23%	2.09	201 / 861	0%	0	0 / 0
intestine	22%	1.80	212 / 966	0%	0.01	2 / 527
skin	17%	1.30	304 / 1809	1%	0.01	4 / 472
stomach	15%	1.24	55 / 359	1%	0.01	2 / 286
bladder	14%	1.57	3 / 21	0%	0.00	1 / 504
blood vessel	13%	0.95	169 / 1335	0%	0	0 / 0
ovary	12%	0.91	21 / 180	0%	0.00	1 / 430
adrenal gland	8%	0.48	20 / 258	0%	0	0 / 230
liver	3%	0.15	6 / 226	0%	0.00	1 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0055074	Biological process	calcium ion homeostasis
GO_0098703	Biological process	calcium ion import across plasma membrane
GO_0006816	Biological process	calcium ion transport
GO_0035809	Biological process	regulation of urine volume
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0051289	Biological process	protein homotetramerization
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0005516	Molecular function	calmodulin binding
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity
GO_0046872	Molecular function	metal ion binding

Gene name	TRPV5
Protein name	Transient receptor potential cation channel subfamily V member 5 Transient receptor potential cation channel subfamily V member 5 (TrpV5) (Calcium transport protein 2) (CaT2) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Osm-9-like TRP channel 3) (OTRPC3)
Synonyms	ECAC1
Description	FUNCTION: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine . Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification . A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity). .
Accessions	ENST00000633067.1 ENST00000439304.5 Q9NQA5 ENST00000442623.1 [Q9NQA5-2] ENST00000633909.1 ENST00000265310.6 [Q9NQA5-1] A0A0J9YXI7 ENST00000633067.1 [Q9NQA5-2] H7C2J6 ENST00000621710.2 [Q9NQA5-1]

TRPV5 report