TRPV3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TRPV3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPV3 at tissue level.

III. Associated gene sets

GO_0098703Biological processcalcium ion import across plasma membrane
GO_0042636Biological processnegative regulation of hair cycle
GO_0009266Biological processresponse to temperature stimulus
GO_0070588Biological processcalcium ion transmembrane transport
GO_0090280Biological processpositive regulation of calcium ion import
GO_0005764Cellular componentlysosome
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0005262Molecular functioncalcium channel activity

IV. Literature review

[source]
Gene nameTRPV3
Protein nameTRPV3 protein
Transient receptor potential cation channel subfamily V member 3
TRPV3 protein (Transient receptor potential cation channel, subfamily V, member 3)
Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)
Synonyms
DescriptionFUNCTION: Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen). .

AccessionsB7ZKP9
ENST00000577016.5
I3L0L5
B2KYM6
Q8NET8
ENST00000616411.4
ENST00000301365.8 [Q8NET8-2]
ENST00000576742.6 [Q8NET8-1]
Q2M3L1
B7ZKP6
ENST00000573539.5
J3KPJ6
A0A087X170
ENST00000571139.5
ENST00000572519.1 [Q8NET8-3]
I3L402
ENST00000381913.8