Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 25% ± 8% | |
endothelial cell | 3 studies | 23% ± 5% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 48% ± 17% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 83% | 1093.73 | 803 / 966 | 49% | 1.92 | 259 / 527 |
brain | 98% | 326.20 | 2594 / 2642 | 30% | 0.53 | 214 / 705 |
prostate | 95% | 234.98 | 233 / 245 | 19% | 0.29 | 97 / 502 |
esophagus | 85% | 114.29 | 1228 / 1445 | 28% | 0.93 | 52 / 183 |
breast | 99% | 282.17 | 455 / 459 | 9% | 0.20 | 97 / 1118 |
uterus | 92% | 116.53 | 156 / 170 | 10% | 0.27 | 48 / 459 |
bladder | 81% | 96.14 | 17 / 21 | 21% | 0.71 | 106 / 504 |
lung | 89% | 138.88 | 516 / 578 | 10% | 0.27 | 121 / 1155 |
adipose | 99% | 247.32 | 1186 / 1204 | 0% | 0 | 0 / 0 |
kidney | 90% | 472.28 | 80 / 89 | 8% | 0.29 | 74 / 901 |
spleen | 97% | 234.72 | 234 / 241 | 0% | 0 | 0 / 0 |
thymus | 83% | 99.18 | 544 / 653 | 11% | 0.35 | 66 / 605 |
skin | 66% | 128.79 | 1191 / 1809 | 16% | 0.39 | 74 / 472 |
peripheral blood | 81% | 594.68 | 751 / 929 | 0% | 0 | 0 / 0 |
stomach | 30% | 29.37 | 106 / 359 | 44% | 2.11 | 127 / 286 |
eye | 0% | 0 | 0 / 0 | 40% | 1.18 | 32 / 80 |
heart | 40% | 39.85 | 344 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 34% | 42.85 | 453 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 20% | 15.91 | 65 / 328 | 8% | 0.14 | 14 / 178 |
tonsil | 0% | 0 | 0 / 0 | 24% | 0.53 | 11 / 45 |
ovary | 10% | 10.06 | 18 / 180 | 2% | 0.03 | 7 / 430 |
muscle | 11% | 8.90 | 88 / 803 | 0% | 0 | 0 / 0 |
adrenal gland | 8% | 7.35 | 20 / 258 | 3% | 0.08 | 7 / 230 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.21 | 3 / 29 |
liver | 4% | 2.48 | 8 / 226 | 2% | 0.04 | 9 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030001 | Biological process | metal ion transport |
GO_0051262 | Biological process | protein tetramerization |
GO_0009636 | Biological process | response to toxic substance |
GO_0098655 | Biological process | monoatomic cation transmembrane transport |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0031526 | Cellular component | brush border membrane |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005262 | Molecular function | calcium channel activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005261 | Molecular function | monoatomic cation channel activity |
Gene name | TRPM6 |
Protein name | Transient receptor potential cation channel subfamily M member 6 (Transient receptor potential cation channel, subfamily M, member 6, isoform CRA_j) (cDNA FLJ25019 fis, clone CBL01642) Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6) |
Synonyms | hCG_1984503 CHAK2 |
Description | FUNCTION: Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region. |
Accessions | ENST00000359047.2 Q96LV9 ENST00000361255.7 [Q9BX84-3] ENST00000449912.6 [Q9BX84-2] ENST00000360774.6 [Q9BX84-1] Q9BX84 |