TRPM6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030001Biological processmetal ion transport
GO_0051262Biological processprotein tetramerization
GO_0009636Biological processresponse to toxic substance
GO_0098655Biological processmonoatomic cation transmembrane transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0031526Cellular componentbrush border membrane
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0005262Molecular functioncalcium channel activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0005261Molecular functionmonoatomic cation channel activity

IV. Literature review

[source]
Gene nameTRPM6
Protein nameTransient receptor potential cation channel subfamily M member 6 (Transient receptor potential cation channel, subfamily M, member 6, isoform CRA_j) (cDNA FLJ25019 fis, clone CBL01642)
Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)
SynonymshCG_1984503
CHAK2
DescriptionFUNCTION: Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.

AccessionsENST00000359047.2
Q96LV9
ENST00000361255.7 [Q9BX84-3]
ENST00000449912.6 [Q9BX84-2]
ENST00000360774.6 [Q9BX84-1]
Q9BX84