TRPC7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TRPC7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPC7 at tissue level.

III. Associated gene sets

GO_0051480Biological processregulation of cytosolic calcium ion concentration
GO_0007338Biological processsingle fertilization
GO_0070588Biological processcalcium ion transmembrane transport
GO_0034703Cellular componentcation channel complex
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005886Cellular componentplasma membrane
GO_0005635Cellular componentnuclear envelope
GO_0070679Molecular functioninositol 1,4,5 trisphosphate binding
GO_0005515Molecular functionprotein binding
GO_0005262Molecular functioncalcium channel activity
GO_0015279Molecular functionstore-operated calcium channel activity

IV. Literature review

[source]
Gene nameTRPC7
Protein nameShort transient receptor potential channel 7 (TrpC7) (Transient receptor protein 7) (TRP-7) (hTRP7)
TRPC7 protein (Transient receptor potential cation channel subfamily C member 7)
Transient receptor potential cation channel subfamily C member 7 (Transient receptor potential channel 7)
SynonymsTRP7
DescriptionFUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. .

AccessionsQ70T25
Q70T24
A1A4Z5
ENST00000513104.6 [Q9HCX4-1]
ENST00000378459.7 [Q9HCX4-3]
ENST00000352189.8 [Q9HCX4-2]
ENST00000503275.6
Q9HCX4
ENST00000514963.5
ENST00000502753.4