TRPC6 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPC6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2793.47	577 / 578	92%	8.86	1067 / 1155
thymus	100%	1305.51	652 / 653	89%	6.86	537 / 605
breast	100%	822.30	459 / 459	85%	2.75	948 / 1118
esophagus	93%	1701.92	1343 / 1445	87%	3.06	159 / 183
uterus	100%	552.12	170 / 170	50%	2.74	231 / 459
prostate	92%	329.64	226 / 245	57%	1.26	288 / 502
kidney	83%	212.30	74 / 89	61%	3.29	552 / 901
intestine	93%	481.53	894 / 966	43%	0.97	226 / 527
bladder	71%	216.81	15 / 21	54%	1.76	270 / 504
skin	86%	388.25	1549 / 1809	33%	0.90	157 / 472
ovary	72%	273.48	129 / 180	42%	0.87	179 / 430
stomach	57%	133.22	205 / 359	56%	1.30	160 / 286
adipose	100%	850.37	1199 / 1204	0%	0	0 / 0
pancreas	12%	20.66	39 / 328	82%	2.15	146 / 178
brain	30%	70.44	798 / 2642	51%	1.37	357 / 705
spleen	77%	209.38	185 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	76%	1.79	34 / 45
blood vessel	73%	206.27	972 / 1335	0%	0	0 / 0
adrenal gland	2%	3.07	4 / 258	47%	1.77	108 / 230
lymph node	0%	0	0 / 0	17%	0.45	5 / 29
liver	0%	0	0 / 226	13%	0.24	51 / 406
heart	10%	22.02	88 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.10	5 / 80
muscle	4%	7.37	32 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006812	Biological process	monoatomic cation transport
GO_0051480	Biological process	regulation of cytosolic calcium ion concentration
GO_0007338	Biological process	single fertilization
GO_0032414	Biological process	positive regulation of ion transmembrane transporter activity
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0051928	Biological process	positive regulation of calcium ion transport
GO_0036057	Cellular component	slit diaphragm
GO_0034703	Cellular component	cation channel complex
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0070679	Molecular function	inositol 1,4,5 trisphosphate binding
GO_0042803	Molecular function	protein homodimerization activity
GO_0015279	Molecular function	store-operated calcium channel activity
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity
GO_0005261	Molecular function	monoatomic cation channel activity

Gene name	TRPC6
Protein name	Transient receptor potential cation channel subfamily C member 6 Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6)
Synonyms	TRP6
Description	FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel . Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C . Seems not to be activated by intracellular calcium store depletion. .
Accessions	ENST00000348423.8 [Q9Y210-2] ENST00000360497.4 [Q9Y210-3] Q9Y210 E9PJN4 ENST00000344327.8 [Q9Y210-1] ENST00000532133.5

TRPC6 report