I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 33% ± 19% | |
| interneuron | 5 studies | 33% ± 15% | |
| GABAergic neuron | 4 studies | 43% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 33% ± 19% | |
| interneuron | 5 studies | 33% ± 15% | |
| GABAergic neuron | 4 studies | 43% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 42% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 87% | 47.58 | 2305 / 2642 | 12% | 0.26 | 84 / 705 |
| liver | 95% | 36.73 | 215 / 226 | 4% | 0.07 | 16 / 406 |
| thymus | 20% | 2.30 | 132 / 653 | 57% | 9.50 | 347 / 605 |
| adrenal gland | 14% | 1.98 | 37 / 258 | 25% | 1.39 | 58 / 230 |
| kidney | 28% | 2.58 | 25 / 89 | 1% | 0.01 | 5 / 901 |
| esophagus | 26% | 12.51 | 378 / 1445 | 1% | 0.01 | 1 / 183 |
| pancreas | 16% | 1.16 | 52 / 328 | 1% | 0.02 | 1 / 178 |
| skin | 15% | 1.17 | 268 / 1809 | 0% | 0.02 | 1 / 472 |
| bladder | 14% | 0.95 | 3 / 21 | 1% | 0.02 | 3 / 504 |
| uterus | 13% | 1.04 | 22 / 170 | 0% | 0.00 | 1 / 459 |
| stomach | 12% | 1.38 | 44 / 359 | 0% | 0.01 | 1 / 286 |
| breast | 10% | 0.92 | 48 / 459 | 1% | 0.01 | 7 / 1118 |
| ovary | 11% | 0.92 | 19 / 180 | 0% | 0 | 0 / 430 |
| adipose | 10% | 0.77 | 119 / 1204 | 0% | 0 | 0 / 0 |
| lung | 8% | 0.66 | 46 / 578 | 1% | 0.02 | 10 / 1155 |
| intestine | 8% | 0.62 | 79 / 966 | 0% | 0 | 0 / 527 |
| prostate | 7% | 0.59 | 18 / 245 | 1% | 0.02 | 3 / 502 |
| blood vessel | 7% | 0.54 | 93 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 6% | 0.44 | 55 / 929 | 0% | 0 | 0 / 0 |
| spleen | 6% | 0.48 | 14 / 241 | 0% | 0 | 0 / 0 |
| heart | 4% | 0.26 | 32 / 861 | 0% | 0 | 0 / 0 |
| muscle | 2% | 0.15 | 15 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051480 | Biological process | regulation of cytosolic calcium ion concentration |
| GO_0070782 | Biological process | phosphatidylserine exposure on apoptotic cell surface |
| GO_0045773 | Biological process | positive regulation of axon extension |
| GO_1902630 | Biological process | regulation of membrane hyperpolarization |
| GO_0051402 | Biological process | neuron apoptotic process |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0045666 | Biological process | positive regulation of neuron differentiation |
| GO_0010800 | Biological process | positive regulation of peptidyl-threonine phosphorylation |
| GO_0050774 | Biological process | negative regulation of dendrite morphogenesis |
| GO_0006816 | Biological process | calcium ion transport |
| GO_0007399 | Biological process | nervous system development |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0030425 | Cellular component | dendrite |
| GO_0034704 | Cellular component | calcium channel complex |
| GO_0030426 | Cellular component | growth cone |
| GO_0034703 | Cellular component | cation channel complex |
| GO_0003779 | Molecular function | actin binding |
| GO_0015279 | Molecular function | store-operated calcium channel activity |
| GO_0070679 | Molecular function | inositol 1,4,5 trisphosphate binding |
| GO_0051117 | Molecular function | ATPase binding |
| GO_0030276 | Molecular function | clathrin binding |
| GO_0042805 | Molecular function | actinin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005262 | Molecular function | calcium channel activity |
| Gene name | TRPC5 |
| Protein name | Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) |
| Synonyms | TRP5 |
| Description | FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity). . |
| Accessions | ENST00000262839.3 Q9UL62 |
