TRPC4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRPC4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	979.78	245 / 245	80%	2.69	401 / 502
kidney	97%	255.45	86 / 89	50%	1.38	446 / 901
pancreas	64%	54.36	210 / 328	58%	1.44	104 / 178
brain	71%	86.93	1867 / 2642	48%	1.47	341 / 705
thymus	92%	138.51	604 / 653	22%	0.44	136 / 605
lung	100%	572.09	577 / 578	12%	0.30	143 / 1155
uterus	99%	1645.70	168 / 170	11%	0.31	51 / 459
ovary	99%	368.94	179 / 180	2%	0.03	7 / 430
blood vessel	100%	538.22	1331 / 1335	0%	0	0 / 0
bladder	90%	221.76	19 / 21	7%	0.16	36 / 504
intestine	85%	355.57	825 / 966	9%	0.16	50 / 527
adipose	85%	139.75	1027 / 1204	0%	0	0 / 0
adrenal gland	69%	67.80	178 / 258	13%	0.25	29 / 230
stomach	57%	337.04	206 / 359	15%	0.42	44 / 286
heart	71%	110.21	615 / 861	0%	0	0 / 0
breast	45%	43.08	208 / 459	3%	0.06	34 / 1118
skin	29%	46.68	518 / 1809	10%	0.22	47 / 472
esophagus	20%	17.83	282 / 1445	15%	0.25	27 / 183
liver	12%	11.72	27 / 226	5%	0.15	21 / 406
muscle	9%	7.56	75 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	7%	0.14	2 / 29
spleen	6%	4.23	14 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.06	2 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051480	Biological process	regulation of cytosolic calcium ion concentration
GO_0070509	Biological process	calcium ion import
GO_0048709	Biological process	oligodendrocyte differentiation
GO_0006816	Biological process	calcium ion transport
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0014051	Biological process	gamma-aminobutyric acid secretion
GO_0005886	Cellular component	plasma membrane
GO_0005911	Cellular component	cell-cell junction
GO_0009986	Cellular component	cell surface
GO_0030863	Cellular component	cortical cytoskeleton
GO_0034704	Cellular component	calcium channel complex
GO_0034703	Cellular component	cation channel complex
GO_0005901	Cellular component	caveola
GO_0016323	Cellular component	basolateral plasma membrane
GO_0045296	Molecular function	cadherin binding
GO_0008013	Molecular function	beta-catenin binding
GO_0015279	Molecular function	store-operated calcium channel activity
GO_0070679	Molecular function	inositol 1,4,5 trisphosphate binding
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity

Gene name	TRPC4
Protein name	TRPC4 protein (Transient receptor potential cation channel subfamily C member 4) Transient receptor potential 4 Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4) TRPC4 protein
Synonyms
Description	FUNCTION: Forms a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion. .
Accessions	Q9UBN4 ENST00000379705.8 [Q9UBN4-1] ENST00000488717.5 [Q9UBN4-7] Q3MHB9 ENST00000358477.6 [Q9UBN4-2] ENST00000426868.6 Q3KR50 ENST00000625583.2 [Q9UBN4-5] ENST00000379673.2 [Q9UBN4-4] Q2M2U7 ENST00000379679.5 [Q9UBN4-6] ENST00000338947.9 [Q9UBN4-6] ENST00000355779.6 [Q9UBN4-3]

TRPC4 report