Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 4 studies | 31% ± 11% | |
| GABAergic neuron | 3 studies | 27% ± 6% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 8% | |
| pericyte | 3 studies | 39% ± 17% |
Insufficient scRNA-seq data for expression of TRPC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 297.89 | 2620 / 2642 | 53% | 1.38 | 371 / 705 |
| bladder | 100% | 359.38 | 21 / 21 | 4% | 0.09 | 18 / 504 |
| lung | 99% | 179.27 | 574 / 578 | 2% | 0.04 | 22 / 1155 |
| uterus | 92% | 88.97 | 157 / 170 | 7% | 0.14 | 30 / 459 |
| breast | 84% | 53.51 | 385 / 459 | 1% | 0.02 | 14 / 1118 |
| adipose | 80% | 44.33 | 967 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 70% | 37.67 | 251 / 359 | 3% | 0.05 | 8 / 286 |
| prostate | 71% | 47.01 | 173 / 245 | 0% | 0.00 | 1 / 502 |
| intestine | 65% | 48.71 | 627 / 966 | 1% | 0.02 | 3 / 527 |
| esophagus | 61% | 59.89 | 886 / 1445 | 4% | 0.07 | 7 / 183 |
| thymus | 65% | 27.79 | 423 / 653 | 0% | 0.00 | 2 / 605 |
| blood vessel | 59% | 49.43 | 782 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 56% | 28.04 | 100 / 180 | 0% | 0.01 | 2 / 430 |
| spleen | 55% | 23.00 | 133 / 241 | 0% | 0 | 0 / 0 |
| kidney | 29% | 11.11 | 26 / 89 | 10% | 0.48 | 92 / 901 |
| heart | 36% | 13.51 | 314 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 2.18 | 9 / 258 | 13% | 0.35 | 29 / 230 |
| skin | 8% | 3.01 | 147 / 1809 | 1% | 0.02 | 4 / 472 |
| liver | 4% | 1.02 | 8 / 226 | 4% | 0.13 | 17 / 406 |
| pancreas | 2% | 0.60 | 6 / 328 | 1% | 0.02 | 1 / 178 |
| muscle | 2% | 0.75 | 18 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.05 | 1 / 45 |
| peripheral blood | 2% | 0.72 | 16 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051480 | Biological process | regulation of cytosolic calcium ion concentration |
| GO_1903244 | Biological process | positive regulation of cardiac muscle hypertrophy in response to stress |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0007338 | Biological process | single fertilization |
| GO_0007602 | Biological process | phototransduction |
| GO_0006816 | Biological process | calcium ion transport |
| GO_0010524 | Biological process | positive regulation of calcium ion transport into cytosol |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0033198 | Biological process | response to ATP |
| GO_0034703 | Cellular component | cation channel complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0070679 | Molecular function | inositol 1,4,5 trisphosphate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005262 | Molecular function | calcium channel activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005227 | Molecular function | calcium-activated cation channel activity |
| GO_0015279 | Molecular function | store-operated calcium channel activity |
| Gene name | TRPC3 |
| Protein name | Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3) Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 3 short isoform Uncharacterized protein TRPC3 Transient receptor potential cation channel subfamily C member 3 variant c |
| Synonyms | TRP3 |
| Description | FUNCTION: Forms a receptor-activated non-selective calcium permeant cation channel . May be operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors . . |
| Accessions | ENST00000513531.1 ENST00000379645.8 [Q13507-2] A7VJS0 D6R902 ENST00000506449.1 ENST00000502968.1 ENST00000264811.9 [Q13507-3] Q13507 Q4W5P7 D6RC49 M1RMB3 J3QTB0 |