TRMT61A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TRMT61A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRMT61A at tissue level.

III. Associated gene sets

GO_0006397Biological processmRNA processing
GO_0030488Biological processtRNA methylation
GO_0031515Cellular componenttRNA (m1A) methyltransferase complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0061953Molecular functionmRNA (adenine-N1-)-methyltransferase activity
GO_0160107Molecular functiontRNA (adenine(58)-N1)-methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTRMT61A
Protein nametRNA (adenine(58)-N(1))-methyltransferase (EC 2.1.1.220)
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)
SynonymsC14orf172
TRM61
DescriptionFUNCTION: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA . Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries . .

AccessionsENST00000389749.9
Q96FX7
ENST00000299202.4
H0Y2Q1
Q96B39