TRMO report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TRMO at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRMO at tissue level.

III. Associated gene sets

GO_0030488Biological processtRNA methylation
GO_0089715Molecular functiontRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTRMO
Protein nametRNA methyltransferase O
Chromosome 9 open reading frame 156, isoform CRA_b (tRNA methyltransferase O)
tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O)
SynonymsC9orf156
hCG_29948
HSPC219
DescriptionFUNCTION: S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) . The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability (By similarity). .

AccessionsQ5T112
Q5T114
ENST00000375118.1
ENST00000375117.8
Q9BU70
ENST00000455506.1
ENST00000375119.8
Q5T111