TRIM46 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRIM46 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1984.44	2635 / 2642	100%	10.00	703 / 705
uterus	92%	571.36	156 / 170	81%	4.38	373 / 459
prostate	74%	254.57	182 / 245	63%	1.78	317 / 502
breast	46%	116.05	210 / 459	91%	4.95	1013 / 1118
lung	47%	101.22	270 / 578	82%	3.28	945 / 1155
stomach	76%	184.64	274 / 359	49%	1.09	139 / 286
bladder	52%	84.57	11 / 21	61%	1.95	306 / 504
ovary	14%	37.88	25 / 180	98%	7.38	420 / 430
skin	32%	124.69	583 / 1809	79%	3.31	373 / 472
esophagus	38%	98.95	542 / 1445	68%	2.26	124 / 183
intestine	57%	131.85	555 / 966	41%	1.01	214 / 527
pancreas	8%	15.47	26 / 328	89%	4.60	159 / 178
spleen	88%	201.12	212 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	2.99	24 / 29
adrenal gland	17%	51.63	44 / 258	66%	8.69	151 / 230
kidney	31%	81.33	28 / 89	36%	1.06	322 / 901
tonsil	0%	0	0 / 0	64%	1.34	29 / 45
blood vessel	64%	245.29	852 / 1335	0%	0	0 / 0
thymus	11%	21.78	75 / 653	44%	1.72	264 / 605
peripheral blood	51%	141.43	470 / 929	0%	0	0 / 0
adipose	31%	78.55	376 / 1204	0%	0	0 / 0
liver	0%	0.58	1 / 226	13%	0.84	51 / 406
heart	3%	6.09	26 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.04	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007409	Biological process	axonogenesis
GO_0030517	Biological process	negative regulation of axon extension
GO_0048490	Biological process	anterograde synaptic vesicle transport
GO_0032880	Biological process	regulation of protein localization
GO_0001764	Biological process	neuron migration
GO_1901953	Biological process	positive regulation of anterograde dense core granule transport
GO_0001578	Biological process	microtubule bundle formation
GO_0099612	Biological process	protein localization to axon
GO_0005856	Cellular component	cytoskeleton
GO_1990769	Cellular component	proximal neuron projection
GO_0043194	Cellular component	axon initial segment
GO_1904115	Cellular component	axon cytoplasm
GO_0044304	Cellular component	main axon
GO_0008270	Molecular function	zinc ion binding

Gene name	TRIM46
Protein name	Tripartite motif containing 46 (Tripartite motif-containing 46, isoform CRA_c) Tripartite motif containing 46 Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein)
Synonyms	TRIFIC hCG_1997323
Description	FUNCTION: Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration. .
Accessions	A0A087WUH1 F5GYK0 Q5VT61 Q7Z4K8 ENST00000543729.5 [Q7Z4K8-4] ENST00000545012.5 ENST00000368383.7 ENST00000368385.8 [Q7Z4K8-2] ENST00000611379.1 ENST00000334634.9 [Q7Z4K8-1] ENST00000368382.5 [Q7Z4K8-5]

TRIM46 report