TRHDE report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
glutamatergic neuron	9 studies	47% ± 23%	Explore
adipocyte	9 studies	54% ± 16%	Explore
GABAergic neuron	5 studies	38% ± 18%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 13%	Explore
fibroblast	4 studies	21% ± 5%	Explore
granule cell	3 studies	48% ± 17%	Explore
glycinergic amacrine cell	3 studies	41% ± 9%	Explore
retinal ganglion cell	3 studies	46% ± 13%	Explore
brush cell	3 studies	27% ± 7%	Explore
interneuron	3 studies	40% ± 17%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	6 studies	42% ± 21%	Explore
adipose	3 studies	28% ± 12%	Explore
kidney	3 studies	25% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	550.04	89 / 89	79%	5.89	715 / 901
pancreas	100%	1677.35	328 / 328	32%	1.02	57 / 178
ovary	100%	884.59	180 / 180	13%	0.57	55 / 430
uterus	95%	660.31	162 / 170	14%	0.62	62 / 459
lung	97%	523.41	563 / 578	8%	0.25	87 / 1155
prostate	90%	386.04	221 / 245	15%	0.26	73 / 502
brain	79%	792.07	2095 / 2642	25%	0.90	178 / 705
bladder	71%	436.43	15 / 21	31%	1.03	157 / 504
intestine	85%	245.17	822 / 966	17%	0.35	88 / 527
spleen	100%	727.70	240 / 241	0%	0	0 / 0
adipose	97%	525.88	1173 / 1204	0%	0	0 / 0
breast	80%	402.66	369 / 459	2%	0.04	21 / 1118
adrenal gland	17%	38.16	43 / 258	48%	2.91	111 / 230
blood vessel	61%	163.89	812 / 1335	0%	0	0 / 0
stomach	36%	62.94	130 / 359	21%	0.58	59 / 286
heart	44%	145.13	378 / 861	0%	0	0 / 0
liver	25%	40.13	57 / 226	17%	0.61	71 / 406
skin	32%	99.59	578 / 1809	7%	1.02	33 / 472
esophagus	19%	31.88	268 / 1445	13%	0.34	24 / 183
thymus	12%	19.15	76 / 653	3%	0.11	21 / 605
muscle	12%	15.76	95 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.23	2 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1