Insufficient scRNA-seq data for expression of TOPAZ1 at single-cell level.
Insufficient scRNA-seq data for expression of TOPAZ1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 35% | 3.48 | 919 / 2642 | 0% | 0 | 0 / 705 |
| prostate | 9% | 0.78 | 22 / 245 | 0% | 0 | 0 / 502 |
| ovary | 6% | 0.74 | 11 / 180 | 0% | 0 | 0 / 430 |
| kidney | 6% | 0.19 | 5 / 89 | 0% | 0.01 | 2 / 901 |
| muscle | 5% | 0.24 | 39 / 803 | 0% | 0 | 0 / 0 |
| stomach | 3% | 0.12 | 11 / 359 | 1% | 0.01 | 2 / 286 |
| thymus | 3% | 0.26 | 21 / 653 | 0% | 0 | 0 / 605 |
| lung | 3% | 0.14 | 17 / 578 | 0% | 0.00 | 3 / 1155 |
| breast | 2% | 0.22 | 10 / 459 | 0% | 0.00 | 2 / 1118 |
| adrenal gland | 2% | 0.10 | 6 / 258 | 0% | 0 | 0 / 230 |
| esophagus | 1% | 0.09 | 21 / 1445 | 1% | 0.01 | 1 / 183 |
| skin | 2% | 0.11 | 36 / 1809 | 0% | 0 | 0 / 472 |
| uterus | 2% | 0.11 | 3 / 170 | 0% | 0 | 0 / 459 |
| peripheral blood | 2% | 0.06 | 15 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 0.06 | 20 / 1335 | 0% | 0 | 0 / 0 |
| intestine | 1% | 0.09 | 14 / 966 | 0% | 0 | 0 / 527 |
| heart | 1% | 0.06 | 12 / 861 | 0% | 0 | 0 / 0 |
| adipose | 1% | 0.06 | 15 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 1% | 0.03 | 3 / 328 | 0% | 0 | 0 / 178 |
| liver | 1% | 0.08 | 2 / 226 | 0% | 0 | 0 / 406 |
| spleen | 1% | 0.02 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0 | 0 / 504 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035234 | Biological process | ectopic germ cell programmed cell death |
| GO_0006915 | Biological process | apoptotic process |
| GO_0048137 | Biological process | spermatocyte division |
| GO_0005829 | Cellular component | cytosol |
| Gene name | TOPAZ1 |
| Protein name | Protein TOPAZ1 (Testis- and ovary-specific PAZ domain-containing protein 1) |
| Synonyms | C3orf77 |
| Description | FUNCTION: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear. . |
| Accessions | ENST00000309765.4 Q8N9V7 |