TNNC1 | OmnibusX

Name	Number of supported studies	Average coverage
heart	4 studies	24% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	67%	1516.26	387 / 578	63%	12.84	727 / 1155
muscle	100%	226924.10	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	50.77	1 / 1
heart	100%	106274.54	860 / 861	0%	0	0 / 0
thymus	4%	100.17	27 / 653	84%	17.25	510 / 605
pancreas	0%	4.18	1 / 328	84%	12.86	150 / 178
ovary	0%	0	0 / 180	70%	20.57	302 / 430
prostate	8%	1200.13	20 / 245	62%	52.56	310 / 502
bladder	0%	0	0 / 21	64%	21.05	322 / 504
intestine	1%	11.99	5 / 966	55%	8.03	292 / 527
stomach	0%	4.40	1 / 359	54%	8.51	154 / 286
uterus	0%	0	0 / 170	45%	50.97	206 / 459
lymph node	0%	0	0 / 0	31%	1.85	9 / 29
tonsil	0%	0	0 / 0	27%	24.47	12 / 45
esophagus	1%	91.70	21 / 1445	25%	4.32	46 / 183
liver	0%	0	0 / 226	25%	6.56	100 / 406
breast	2%	124.31	9 / 459	18%	2.16	198 / 1118
adrenal gland	3%	73.29	9 / 258	11%	1.73	26 / 230
kidney	2%	28.91	2 / 89	12%	1.51	105 / 901
skin	1%	109.24	18 / 1809	6%	1.44	29 / 472
blood vessel	4%	465.28	57 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.15	3 / 80
adipose	2%	50.84	29 / 1204	0%	0	0 / 0
peripheral blood	2%	144.03	22 / 929	0%	0	0 / 0
brain	0%	5.49	9 / 2642	2%	0.10	14 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0010038	Biological process	response to metal ion
GO_0003009	Biological process	skeletal muscle contraction
GO_0002086	Biological process	diaphragm contraction
GO_0006937	Biological process	regulation of muscle contraction
GO_0043462	Biological process	regulation of ATP-dependent activity
GO_0060048	Biological process	cardiac muscle contraction
GO_0055010	Biological process	ventricular cardiac muscle tissue morphogenesis
GO_0014883	Biological process	transition between fast and slow fiber
GO_0032972	Biological process	regulation of muscle filament sliding speed
GO_1990584	Cellular component	cardiac Troponin complex
GO_0005861	Cellular component	troponin complex
GO_0005829	Cellular component	cytosol
GO_0042803	Molecular function	protein homodimerization activity
GO_0031013	Molecular function	troponin I binding
GO_0051015	Molecular function	actin filament binding
GO_0048306	Molecular function	calcium-dependent protein binding
GO_0031014	Molecular function	troponin T binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	TNNC1
Protein name	Troponin C, slow skeletal and cardiac muscles (TN-C) Troponin C, slow skeletal and cardiac muscles
Synonyms	hCG_42573 TNNC
Description	FUNCTION: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. FUNCTION: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. . FUNCTION: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. .
Accessions	P63316 ENST00000232975.8 Q6FH91 ENST00000496590.1 C9JDI3

TNNC1 report