TNK1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TNK1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNK1 at tissue level.

III. Associated gene sets

GO_0006468Biological processprotein phosphorylation
GO_0046777Biological processprotein autophosphorylation
GO_0016020Cellular componentmembrane
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0004713Molecular functionprotein tyrosine kinase activity
GO_0004715Molecular functionnon-membrane spanning protein tyrosine kinase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameTNK1
Protein nameNon-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)
Alternative protein TNK1
non-specific protein-tyrosine kinase (EC 2.7.10.2)
Tyrosine kinase non receptor 1
Synonyms
DescriptionFUNCTION: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction. .

AccessionsENST00000639010.1 [Q13470-2]
Q13470
I3L334
L8E7K1
ENST00000570896.5 [Q13470-2]
ENST00000576812.5 [Q13470-1]
ENST00000639430.1 [Q13470-1]
ENST00000688331.1 [Q13470-2]
ENST00000576207.2
ENST00000576716.1
U3KPR9