TMPRSS15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TMPRSS15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMPRSS15 at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0005903Cellular componentbrush border
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameTMPRSS15
Protein nameEnteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain]
Transmembrane serine protease 15
SynonymsENTK
PRSS7
DescriptionFUNCTION: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

AccessionsENST00000284885.8
ENST00000422787.1
P98073
E9PG70