TMOD4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TMOD4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMOD4 at tissue level.

III. Associated gene sets

GO_0007015Biological processactin filament organization
GO_0051694Biological processpointed-end actin filament capping
GO_0006936Biological processmuscle contraction
GO_0030239Biological processmyofibril assembly
GO_0030016Cellular componentmyofibril
GO_0005856Cellular componentcytoskeleton
GO_0005865Cellular componentstriated muscle thin filament
GO_0005523Molecular functiontropomyosin binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameTMOD4
Protein nameTropomodulin 4
Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod)
Tropomodulin 4 (Muscle), isoform CRA_b (cDNA FLJ35381 fis, clone SKMUS2007359, highly similar to Tropomodulin 4 (muscle))
SynonymshCG_1741228
DescriptionFUNCTION: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.

AccessionsENST00000295314.9 [Q9NZQ9-1]
ENST00000463543.5
ENST00000466891.5
K7ES04
Q8N706
Q5JR82
ENST00000441701.1
K7EQW4
Q9NZQ9