TMEM86A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TMEM86A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMEM86A at tissue level.

III. Associated gene sets

GO_0006629Biological processlipid metabolic process
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0016787Molecular functionhydrolase activity
GO_0005515Molecular functionprotein binding
GO_0047408Molecular functionalkenylglycerophosphocholine hydrolase activity

IV. Literature review

[source]
Gene nameTMEM86A
Protein nameLysoplasmalogenase TMEM86A (EC 3.3.2.2) (Transmembrane protein 86A)
Synonyms
DescriptionFUNCTION: Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen . Plays an important role in lysoplasmalogen metabolism in the adipocyte tissue and macrophages . .

AccessionsQ8N2M4
ENST00000280734.3