Insufficient scRNA-seq data for expression of TMEM74 at single-cell level.
Insufficient scRNA-seq data for expression of TMEM74 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 124.50 | 2638 / 2642 | 57% | 1.80 | 402 / 705 |
liver | 85% | 37.04 | 192 / 226 | 34% | 0.80 | 140 / 406 |
esophagus | 98% | 57.40 | 1417 / 1445 | 1% | 0.04 | 1 / 183 |
blood vessel | 95% | 49.83 | 1267 / 1335 | 0% | 0 | 0 / 0 |
muscle | 88% | 37.11 | 706 / 803 | 0% | 0 | 0 / 0 |
adipose | 84% | 28.73 | 1009 / 1204 | 0% | 0 | 0 / 0 |
intestine | 79% | 65.18 | 762 / 966 | 2% | 0.03 | 8 / 527 |
pancreas | 74% | 20.90 | 244 / 328 | 2% | 0.05 | 4 / 178 |
breast | 69% | 20.48 | 318 / 459 | 4% | 0.08 | 44 / 1118 |
heart | 72% | 24.93 | 617 / 861 | 0% | 0 | 0 / 0 |
uterus | 60% | 14.59 | 102 / 170 | 10% | 0.24 | 47 / 459 |
skin | 62% | 15.06 | 1128 / 1809 | 5% | 0.09 | 25 / 472 |
thymus | 63% | 15.32 | 409 / 653 | 4% | 0.10 | 27 / 605 |
bladder | 57% | 18.62 | 12 / 21 | 3% | 0.17 | 16 / 504 |
prostate | 59% | 13.92 | 145 / 245 | 0% | 0 | 0 / 502 |
stomach | 48% | 24.17 | 172 / 359 | 3% | 0.07 | 8 / 286 |
lung | 28% | 5.31 | 163 / 578 | 7% | 0.16 | 80 / 1155 |
ovary | 26% | 5.68 | 46 / 180 | 2% | 0.04 | 10 / 430 |
spleen | 24% | 4.32 | 57 / 241 | 0% | 0 | 0 / 0 |
kidney | 13% | 2.17 | 12 / 89 | 1% | 0.03 | 13 / 901 |
adrenal gland | 8% | 1.34 | 21 / 258 | 5% | 0.08 | 12 / 230 |
tonsil | 0% | 0 | 0 / 0 | 11% | 0.30 | 5 / 45 |
peripheral blood | 5% | 1.17 | 51 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0016236 | Biological process | macroautophagy |
GO_0051867 | Biological process | general adaptation syndrome, behavioral process |
GO_0000421 | Cellular component | autophagosome membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0005515 | Molecular function | protein binding |
GO_0044325 | Molecular function | transmembrane transporter binding |
Gene name | TMEM74 |
Protein name | Transmembrane protein 74 |
Synonyms | |
Description | FUNCTION: Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction. . |
Accessions | Q96NL1 ENST00000297459.4 |