TMEM63B | OmnibusX

Name	Number of supported studies	Average coverage
type I pneumocyte	12 studies	31% ± 6%	Explore
type II pneumocyte	7 studies	27% ± 11%	Explore
endothelial cell	5 studies	26% ± 10%	Explore
glutamatergic neuron	5 studies	40% ± 16%	Explore
epithelial cell	5 studies	26% ± 6%	Explore
GABAergic neuron	5 studies	32% ± 16%	Explore
neuron	4 studies	22% ± 5%	Explore
interneuron	4 studies	26% ± 15%	Explore
oligodendrocyte precursor cell	3 studies	20% ± 4%	Explore
basal cell	3 studies	19% ± 2%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	25% ± 11%	Explore
lung	3 studies	17% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3133.54	1445 / 1445	100%	93.26	183 / 183
liver	100%	3208.98	226 / 226	100%	52.78	406 / 406
lung	100%	6165.70	578 / 578	100%	74.70	1154 / 1155
skin	100%	5052.51	1809 / 1809	100%	65.17	471 / 472
intestine	100%	3115.27	966 / 966	100%	51.63	525 / 527
prostate	100%	3034.91	245 / 245	100%	50.13	500 / 502
uterus	100%	2238.75	170 / 170	100%	59.21	457 / 459
breast	100%	2164.32	459 / 459	100%	68.76	1113 / 1118
brain	99%	3338.59	2625 / 2642	100%	50.19	704 / 705
stomach	100%	2895.38	359 / 359	99%	55.01	283 / 286
thymus	100%	2900.21	653 / 653	99%	43.43	598 / 605
bladder	100%	2914.67	21 / 21	98%	57.27	496 / 504
ovary	100%	1949.03	180 / 180	98%	43.83	423 / 430
kidney	100%	2386.10	89 / 89	98%	38.35	881 / 901
adrenal gland	100%	2918.28	258 / 258	96%	46.44	221 / 230
pancreas	95%	1096.71	310 / 328	99%	43.75	176 / 178
muscle	100%	4568.67	803 / 803	0%	0	0 / 0
spleen	100%	1604.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	62.41	45 / 45
ureter	0%	0	0 / 0	100%	45.57	1 / 1
adipose	100%	2033.97	1203 / 1204	0%	0	0 / 0
blood vessel	99%	1759.02	1325 / 1335	0%	0	0 / 0
peripheral blood	99%	1812.61	921 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	53.64	79 / 80
heart	97%	2380.80	837 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	15.30	26 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007605	Biological process	sensory perception of sound
GO_0098655	Biological process	monoatomic cation transmembrane transport
GO_0160069	Biological process	surfactant secretion
GO_0031901	Cellular component	early endosome membrane
GO_0015629	Cellular component	actin cytoskeleton
GO_0097233	Cellular component	alveolar lamellar body membrane
GO_0005886	Cellular component	plasma membrane
GO_0140135	Molecular function	mechanosensitive monoatomic cation channel activity
GO_1990760	Molecular function	osmolarity-sensing monoatomic cation channel activity
GO_0008381	Molecular function	mechanosensitive monoatomic ion channel activity
GO_0005227	Molecular function	calcium-activated cation channel activity

Gene name	TMEM63B
Protein name	Transmembrane protein 63B CSC1-like protein 2 (Transmembrane protein 63B)
Synonyms	C6orf110
Description	FUNCTION: Acts as an osmosensitive calcium-permeable cation channel (By similarity). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion . Acts as an inner ear osmosensor, essential for normal hearing and survival of inner ear outer hair cells (OHCs). Mediates calcium-dependent regulatory volume decrease in OHCs which is necessary for their survival. Required for the maintenance of the morphological integrity of OHCs under hypotonic conditions. Mediates hypo-osmolarity-induced calcium influx, leading to activation of calcium-dependent potassium channels required for the maintenance of OHC morphology (By similarity). .
Accessions	ENST00000533121.1 ENST00000371893.6 Q5T3F8 H0YCP6 H3BLW6 ENST00000259746.13 [Q5T3F8-1] ENST00000323267.11 [Q5T3F8-1] E9PNG1 ENST00000532634.5 H0YDJ6 ENST00000497371.6

TMEM63B report