I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 32% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 32% ± 11% |
Insufficient scRNA-seq data for expression of TMEM25 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2029.28 | 245 / 245 | 100% | 28.93 | 502 / 502 |
| brain | 100% | 3700.68 | 2634 / 2642 | 100% | 24.92 | 702 / 705 |
| thymus | 100% | 1608.98 | 652 / 653 | 99% | 21.98 | 599 / 605 |
| ovary | 100% | 2292.53 | 180 / 180 | 97% | 15.48 | 417 / 430 |
| breast | 94% | 1726.92 | 432 / 459 | 98% | 36.95 | 1097 / 1118 |
| adrenal gland | 100% | 2612.49 | 258 / 258 | 91% | 23.04 | 209 / 230 |
| pancreas | 99% | 933.63 | 325 / 328 | 92% | 10.60 | 163 / 178 |
| uterus | 100% | 1815.89 | 170 / 170 | 90% | 10.93 | 411 / 459 |
| lung | 96% | 994.19 | 556 / 578 | 89% | 12.39 | 1026 / 1155 |
| kidney | 100% | 1750.87 | 89 / 89 | 85% | 11.43 | 765 / 901 |
| bladder | 100% | 1513.62 | 21 / 21 | 71% | 10.87 | 358 / 504 |
| esophagus | 97% | 1286.49 | 1395 / 1445 | 70% | 6.22 | 128 / 183 |
| stomach | 99% | 1132.23 | 357 / 359 | 35% | 3.21 | 101 / 286 |
| liver | 91% | 1461.18 | 206 / 226 | 37% | 3.19 | 152 / 406 |
| intestine | 95% | 1666.28 | 922 / 966 | 28% | 2.31 | 150 / 527 |
| skin | 77% | 579.63 | 1392 / 1809 | 31% | 2.81 | 145 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.34 | 1 / 1 |
| blood vessel | 100% | 2103.92 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 98% | 640.05 | 236 / 241 | 0% | 0 | 0 / 0 |
| adipose | 86% | 655.77 | 1035 / 1204 | 0% | 0 | 0 / 0 |
| heart | 82% | 556.36 | 709 / 861 | 0% | 0 | 0 / 0 |
| muscle | 72% | 414.14 | 577 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 5.30 | 32 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 3.29 | 16 / 29 |
| eye | 0% | 0 | 0 / 0 | 34% | 2.72 | 27 / 80 |
| peripheral blood | 11% | 52.84 | 105 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0090394 | Biological process | negative regulation of excitatory postsynaptic potential |
| GO_0031647 | Biological process | regulation of protein stability |
| GO_0005764 | Cellular component | lysosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005770 | Cellular component | late endosome |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMEM25 |
| Protein name | Transmembrane protein 25 |
| Synonyms | UNQ2531/PRO6030 |
| Description | FUNCTION: In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability. . |
| Accessions | E9PID6 ENST00000532762.5 ENST00000527267.1 ENST00000411589.6 [Q86YD3-2] ENST00000533137.5 E9PKP3 H0YD63 H0YC87 E9PIR4 ENST00000534181.5 ENST00000533102.5 E9PIE6 Q86YD3 ENST00000526973.5 ENST00000442938.6 [Q86YD3-5] ENST00000528373.5 ENST00000354064.11 [Q86YD3-3] ENST00000313236.10 [Q86YD3-1] ENST00000533689.1 ENST00000525118.5 ENST00000354284.8 [Q86YD3-4] E9PK43 E9PIT4 E9PI73 ENST00000359862.8 [Q86YD3-2] ENST00000524725.5 [Q86YD3-2] E9PK88 ENST00000526853.1 |
