I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 34% ± 9% | |
| GABAergic neuron | 3 studies | 25% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 34% ± 9% | |
| GABAergic neuron | 3 studies | 25% ± 7% |
Insufficient scRNA-seq data for expression of TMEM182 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 95% | 150.36 | 621 / 653 | 97% | 3.06 | 586 / 605 |
| stomach | 95% | 116.14 | 341 / 359 | 97% | 3.39 | 276 / 286 |
| brain | 94% | 175.14 | 2471 / 2642 | 97% | 2.80 | 684 / 705 |
| breast | 93% | 141.36 | 429 / 459 | 97% | 3.33 | 1082 / 1118 |
| pancreas | 92% | 108.91 | 303 / 328 | 97% | 3.05 | 173 / 178 |
| prostate | 96% | 146.54 | 236 / 245 | 93% | 2.50 | 468 / 502 |
| ovary | 89% | 109.84 | 161 / 180 | 99% | 4.10 | 427 / 430 |
| bladder | 90% | 166.38 | 19 / 21 | 96% | 3.39 | 484 / 504 |
| kidney | 94% | 150.46 | 84 / 89 | 92% | 3.20 | 828 / 901 |
| intestine | 87% | 100.38 | 837 / 966 | 96% | 3.34 | 505 / 527 |
| adrenal gland | 95% | 170.15 | 245 / 258 | 84% | 3.48 | 193 / 230 |
| lung | 77% | 91.71 | 446 / 578 | 99% | 4.67 | 1146 / 1155 |
| uterus | 76% | 72.26 | 130 / 170 | 96% | 3.58 | 440 / 459 |
| esophagus | 66% | 66.99 | 960 / 1445 | 97% | 3.58 | 177 / 183 |
| skin | 59% | 80.74 | 1060 / 1809 | 89% | 3.15 | 422 / 472 |
| liver | 87% | 213.07 | 196 / 226 | 51% | 1.46 | 209 / 406 |
| muscle | 100% | 3030.31 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.66 | 1 / 1 |
| heart | 100% | 4807.20 | 857 / 861 | 0% | 0 | 0 / 0 |
| spleen | 96% | 113.16 | 231 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 92% | 139.43 | 1225 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 1.80 | 26 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 2.75 | 40 / 45 |
| adipose | 85% | 108.81 | 1021 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 57% | 1.19 | 46 / 80 |
| peripheral blood | 26% | 58.48 | 242 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0014906 | Biological process | myotube cell development involved in skeletal muscle regeneration |
| GO_0014908 | Biological process | myotube differentiation involved in skeletal muscle regeneration |
| GO_1901740 | Biological process | negative regulation of myoblast fusion |
| GO_0007517 | Biological process | muscle organ development |
| GO_0045662 | Biological process | negative regulation of myoblast differentiation |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMEM182 |
| Protein name | Transmembrane protein 182 |
| Synonyms | UNQ6974/PRO21957 |
| Description | FUNCTION: Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (By similarity). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (By similarity). . |
| Accessions | A0A1W2PS41 ENST00000486293.1 ENST00000409528.5 [Q6ZP80-2] B8ZZ71 A0A1W2PQA2 ENST00000639249.1 A0A494C0U9 ENST00000409173.5 C9IYX5 ENST00000640575.2 ENST00000488134.5 ENST00000412401.3 [Q6ZP80-1] Q6ZP80 A0A494C149 ENST00000454536.5 |
