TMC1 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	3 studies	37% ± 21%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TMC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	96%	52.62	236 / 245	40%	0.91	203 / 502
brain	97%	35.47	2565 / 2642	35%	0.66	246 / 705
bladder	100%	66.71	21 / 21	11%	0.21	53 / 504
kidney	99%	42.11	88 / 89	0%	0.02	3 / 901
uterus	87%	17.86	148 / 170	10%	0.20	48 / 459
ovary	77%	11.58	139 / 180	16%	0.32	70 / 430
adipose	89%	18.70	1077 / 1204	0%	0	0 / 0
breast	83%	15.38	382 / 459	2%	0.05	24 / 1118
skin	65%	10.35	1171 / 1809	1%	0.02	6 / 472
muscle	66%	31.08	530 / 803	0%	0	0 / 0
esophagus	59%	63.34	854 / 1445	4%	0.08	8 / 183
adrenal gland	47%	7.71	122 / 258	0%	0	0 / 230
thymus	42%	4.21	273 / 653	1%	0.02	4 / 605
intestine	41%	4.55	395 / 966	1%	0.01	3 / 527
blood vessel	31%	3.75	419 / 1335	0%	0	0 / 0
stomach	25%	2.76	88 / 359	1%	0.02	4 / 286
lung	21%	2.02	120 / 578	5%	0.10	52 / 1155
heart	24%	2.42	207 / 861	0%	0	0 / 0
liver	7%	0.60	16 / 226	0%	0.00	1 / 406
peripheral blood	5%	0.45	49 / 929	0%	0	0 / 0
spleen	5%	0.32	11 / 241	0%	0	0 / 0
pancreas	2%	0.16	8 / 328	1%	0.02	1 / 178
tonsil	0%	0	0 / 0	2%	0.05	1 / 45
eye	0%	0	0 / 0	1%	0.04	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0060005	Biological process	vestibular reflex
GO_0050910	Biological process	detection of mechanical stimulus involved in sensory perception of sound
GO_1903169	Biological process	regulation of calcium ion transmembrane transport
GO_0060117	Biological process	auditory receptor cell development
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0009897	Cellular component	external side of plasma membrane
GO_0032426	Cellular component	stereocilium tip
GO_0005245	Molecular function	voltage-gated calcium channel activity
GO_0008381	Molecular function	mechanosensitive monoatomic ion channel activity

Gene name	TMC1
Protein name	Transmembrane channel-like protein Transmembrane channel-like protein 1 (Transmembrane cochlear-expressed protein 1)
Synonyms
Description	FUNCTION: Probable ion channel required for the normal function of cochlear hair cells. .
Accessions	ENST00000340019.4 ENST00000645773.1 ENST00000486417.5 A0A2R8Y434 A0A2R8YDK2 Q8TDI8 ENST00000645208.2 A0A494C0T8 A0A2R8YDJ2 A4FU59 ENST00000644967.1 ENST00000645053.1 A0A2R8YGM2 ENST00000646619.1 Q3MI88 A0A2R8YDA3 A5D8Y1 ENST00000651183.1 ENST00000297784.10 A4FUA6

TMC1 report