TK1 | OmnibusX

Name	Number of supported studies	Average coverage
T cell	6 studies	27% ± 9%	Explore
plasmablast	5 studies	39% ± 17%	Explore
transit amplifying cell	5 studies	38% ± 14%	Explore
B cell	4 studies	28% ± 10%	Explore
epithelial cell	4 studies	25% ± 8%	Explore
erythrocyte	4 studies	29% ± 14%	Explore
CD4-positive, alpha-beta T cell	4 studies	35% ± 8%	Explore
CD8-positive, alpha-beta T cell	4 studies	32% ± 6%	Explore
erythroblast	3 studies	40% ± 20%	Explore
natural killer cell	3 studies	32% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	24% ± 6%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	35% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1179.97	1438 / 1445	99%	170.74	182 / 183
lung	99%	730.65	573 / 578	92%	159.80	1064 / 1155
stomach	89%	766.16	321 / 359	98%	137.55	279 / 286
skin	92%	1996.53	1671 / 1809	94%	111.35	446 / 472
intestine	89%	730.13	855 / 966	97%	155.19	513 / 527
breast	84%	310.08	385 / 459	95%	133.04	1063 / 1118
pancreas	94%	232.54	307 / 328	84%	71.12	150 / 178
liver	94%	409.81	213 / 226	66%	56.10	269 / 406
kidney	100%	721.13	89 / 89	57%	35.52	518 / 901
bladder	57%	154.48	12 / 21	95%	171.89	480 / 504
uterus	44%	108.26	75 / 170	99%	278.49	456 / 459
prostate	86%	291.19	211 / 245	42%	22.77	213 / 502
ovary	22%	64.18	39 / 180	97%	130.79	415 / 430
lymph node	0%	0	0 / 0	100%	249.80	29 / 29
tonsil	0%	0	0 / 0	100%	375.38	45 / 45
ureter	0%	0	0 / 0	100%	94.11	1 / 1
spleen	99%	901.20	238 / 241	0%	0	0 / 0
thymus	59%	135.46	386 / 653	30%	26.43	184 / 605
peripheral blood	89%	1535.65	827 / 929	0%	0	0 / 0
brain	45%	131.34	1201 / 2642	29%	16.09	201 / 705
adrenal gland	55%	170.49	141 / 258	13%	9.91	29 / 230
adipose	62%	191.18	752 / 1204	0%	0	0 / 0
muscle	58%	118.15	466 / 803	0%	0	0 / 0
blood vessel	55%	142.10	733 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	45%	19.12	36 / 80
heart	30%	68.28	256 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006139	Biological process	nucleobase-containing compound metabolic process
GO_0046105	Biological process	thymidine biosynthetic process
GO_0046104	Biological process	thymidine metabolic process
GO_0009157	Biological process	deoxyribonucleoside monophosphate biosynthetic process
GO_0051289	Biological process	protein homotetramerization
GO_1904860	Biological process	DNA synthesis involved in mitotic DNA replication
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0004797	Molecular function	thymidine kinase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding
GO_0005524	Molecular function	ATP binding

Gene name	TK1
Protein name	Thymidine kinase, cytosolic (EC 2.7.1.21) Thymidine kinase (EC 2.7.1.21)
Synonyms
Description	FUNCTION: Cell-cycle-regulated enzyme of importance in nucleotide metabolism . Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate . Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT) . .
Accessions	ENST00000301634.12 K7ERV3 ENST00000590862.5 ENST00000588734.5 B5BU32 B5BUF9 ENST00000590430.5 ENST00000586613.1 K7ERJ1 K7ENW5 K7ES52 P04183

TK1 report