TIMP4 | OmnibusX

Name	Number of supported studies	Average coverage
adipocyte	3 studies	22% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TIMP4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	95%	7711.80	437 / 459	48%	11.18	535 / 1118
brain	39%	619.33	1026 / 2642	100%	262.66	702 / 705
intestine	70%	705.07	673 / 966	65%	7.94	342 / 527
adrenal gland	52%	422.46	134 / 258	61%	12.40	140 / 230
bladder	67%	554.48	14 / 21	43%	6.34	219 / 504
stomach	47%	422.75	170 / 359	54%	6.43	154 / 286
adipose	100%	9498.81	1203 / 1204	0%	0	0 / 0
blood vessel	95%	2404.46	1265 / 1335	0%	0	0 / 0
thymus	76%	1638.94	497 / 653	11%	1.20	69 / 605
heart	84%	1143.52	726 / 861	0%	0	0 / 0
prostate	36%	263.67	87 / 245	43%	6.30	217 / 502
esophagus	57%	734.53	819 / 1445	21%	1.70	39 / 183
pancreas	6%	29.27	20 / 328	66%	8.32	117 / 178
muscle	63%	540.63	503 / 803	0%	0	0 / 0
lung	41%	397.50	238 / 578	20%	1.95	236 / 1155
uterus	45%	361.13	76 / 170	15%	2.82	69 / 459
skin	46%	411.71	826 / 1809	13%	2.93	61 / 472
kidney	9%	98.39	8 / 89	34%	3.56	310 / 901
ovary	16%	115.33	29 / 180	23%	3.26	100 / 430
spleen	22%	122.65	52 / 241	0%	0	0 / 0
liver	0%	1.83	1 / 226	6%	1.23	25 / 406
tonsil	0%	0	0 / 0	2%	0.09	1 / 45
peripheral blood	2%	9.60	14 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0009725	Biological process	response to hormone
GO_0010951	Biological process	negative regulation of endopeptidase activity
GO_0051045	Biological process	negative regulation of membrane protein ectodomain proteolysis
GO_0007219	Biological process	Notch signaling pathway
GO_0008150	Biological process	biological_process
GO_0034097	Biological process	response to cytokine
GO_0005615	Cellular component	extracellular space
GO_0031012	Cellular component	extracellular matrix
GO_0002020	Molecular function	protease binding
GO_0008191	Molecular function	metalloendopeptidase inhibitor activity
GO_0046872	Molecular function	metal ion binding

Gene name	TIMP4
Protein name	Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
Synonyms
Description	FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Accessions	ENST00000287814.5 Q99727

TIMP4 report