THRSP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of THRSP at tissue level.

III. Associated gene sets

GO_0006629Biological processlipid metabolic process
GO_0046890Biological processregulation of lipid biosynthetic process
GO_0010866Biological processregulation of triglyceride biosynthetic process
GO_0009617Biological processresponse to bacterium
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0042803Molecular functionprotein homodimerization activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0140678Molecular functionmolecular function inhibitor activity

IV. Literature review

[source]
Gene nameTHRSP
Protein nameThyroid hormone-inducible hepatic protein (Spot 14 protein) (S14) (SPOT14)
Synonyms
DescriptionFUNCTION: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. .

AccessionsQ92748
ENST00000281030.2