TGM1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TGM1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TGM1 at tissue level.

III. Associated gene sets

GO_0030216Biological processkeratinocyte differentiation
GO_0031424Biological processkeratinization
GO_0018149Biological processpeptide cross-linking
GO_0045787Biological processpositive regulation of cell cycle
GO_0036211Biological processprotein modification process
GO_0010838Biological processpositive regulation of keratinocyte proliferation
GO_0043163Biological processcell envelope organization
GO_0001533Cellular componentcornified envelope
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003810Molecular functionprotein-glutamine gamma-glutamyltransferase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameTGM1
Protein nameTransglutaminase 1
protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13)
Transglutaminase 1 isoform
Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)
SynonymsKTG
DescriptionFUNCTION: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation . .

AccessionsENST00000559136.1
A0A0G2JL93
ENST00000206765.11 [P22735-1]
ENST00000560443.1
H0YN27
H0YMQ8
H0YKI6
P22735
ENST00000559669.1
H0YLJ6
ENST00000561067.1
H0YLT9
ENST00000646057.1 [P22735-2]
ENST00000558074.1
ENST00000642845.2 [P22735-1]
H0YNM4
ENST00000560226.1
G1APU8
ENST00000544573.5 [P22735-2]
ENST00000560478.1