Insufficient scRNA-seq data for expression of TFF2 at single-cell level.
Insufficient scRNA-seq data for expression of TFF2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 70% | 253.16 | 230 / 328 | 87% | 1123.12 | 154 / 178 |
| stomach | 96% | 43894.49 | 344 / 359 | 60% | 405.66 | 173 / 286 |
| thymus | 98% | 142.22 | 642 / 653 | 2% | 0.48 | 13 / 605 |
| intestine | 34% | 93.99 | 326 / 966 | 50% | 243.30 | 261 / 527 |
| liver | 64% | 36.45 | 144 / 226 | 13% | 28.57 | 52 / 406 |
| esophagus | 21% | 29.14 | 302 / 1445 | 42% | 270.36 | 76 / 183 |
| bladder | 29% | 4.43 | 6 / 21 | 29% | 34.43 | 148 / 504 |
| breast | 24% | 16.59 | 110 / 459 | 5% | 1.37 | 55 / 1118 |
| uterus | 16% | 2.82 | 27 / 170 | 11% | 18.97 | 51 / 459 |
| ovary | 14% | 2.17 | 26 / 180 | 12% | 4.03 | 51 / 430 |
| lung | 5% | 13.62 | 30 / 578 | 20% | 206.50 | 231 / 1155 |
| adipose | 20% | 31.67 | 237 / 1204 | 0% | 0 | 0 / 0 |
| skin | 10% | 2.74 | 186 / 1809 | 8% | 4.72 | 40 / 472 |
| adrenal gland | 18% | 3.36 | 47 / 258 | 0% | 0 | 0 / 230 |
| prostate | 17% | 3.25 | 41 / 245 | 0% | 0.03 | 2 / 502 |
| spleen | 17% | 3.02 | 40 / 241 | 0% | 0 | 0 / 0 |
| kidney | 11% | 2.53 | 10 / 89 | 4% | 0.82 | 34 / 901 |
| peripheral blood | 7% | 1.23 | 62 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 7% | 2.73 | 87 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 5% | 1.83 | 38 / 803 | 0% | 0 | 0 / 0 |
| brain | 4% | 0.79 | 107 / 2642 | 0% | 0.01 | 1 / 705 |
| heart | 4% | 3.06 | 36 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.20 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060455 | Biological process | negative regulation of gastric acid secretion |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0030277 | Biological process | maintenance of gastrointestinal epithelium |
| GO_0005615 | Cellular component | extracellular space |
| GO_0031723 | Molecular function | CXCR4 chemokine receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TFF2 |
| Protein name | Trefoil factor 2 (Spasmolysin) (Spasmolytic polypeptide) (SP) |
| Synonyms | SML1 |
| Description | FUNCTION: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). . |
| Accessions | Q03403 ENST00000291526.5 |