TFF2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TFF2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TFF2 at tissue level.

III. Associated gene sets

GO_0060455Biological processnegative regulation of gastric acid secretion
GO_0070098Biological processchemokine-mediated signaling pathway
GO_0030277Biological processmaintenance of gastrointestinal epithelium
GO_0005615Cellular componentextracellular space
GO_0031723Molecular functionCXCR4 chemokine receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTFF2
Protein nameTrefoil factor 2 (Spasmolysin) (Spasmolytic polypeptide) (SP)
SynonymsSML1
DescriptionFUNCTION: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). .

AccessionsQ03403
ENST00000291526.5