TFDP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TFDP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TFDP3 at tissue level.

III. Associated gene sets

GO_2000134Biological processnegative regulation of G1/S transition of mitotic cell cycle
GO_0006974Biological processDNA damage response
GO_0043433Biological processnegative regulation of DNA-binding transcription factor activity
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005667Cellular componenttranscription regulator complex
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0140416Molecular functiontranscription regulator inhibitor activity
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameTFDP3
Protein nameTranscription factor Dp family member 3 (Cancer/testis antigen 30) (CT30) (Hepatocellular carcinoma-associated antigen 661)
SynonymsHCA661
DP4
DescriptionFUNCTION: Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase. .

AccessionsENST00000310125.5
Q5H9I0