TDRD5 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	21% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TDRD5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	85%	286.01	391 / 459	92%	10.33	1027 / 1118
thymus	99%	139.13	644 / 653	33%	1.00	199 / 605
prostate	76%	79.11	185 / 245	49%	1.18	247 / 502
stomach	57%	27.26	204 / 359	54%	2.06	155 / 286
bladder	52%	48.62	11 / 21	59%	3.23	295 / 504
kidney	100%	140.21	89 / 89	9%	0.24	81 / 901
esophagus	34%	23.03	491 / 1445	73%	4.68	134 / 183
intestine	49%	45.74	471 / 966	58%	1.92	306 / 527
pancreas	41%	15.00	133 / 328	49%	2.01	88 / 178
ovary	16%	9.69	28 / 180	74%	2.86	320 / 430
adrenal gland	55%	37.38	141 / 258	26%	0.91	59 / 230
lung	19%	7.01	109 / 578	58%	4.26	675 / 1155
tonsil	0%	0	0 / 0	76%	4.54	34 / 45
brain	68%	101.56	1805 / 2642	7%	0.12	48 / 705
skin	59%	39.72	1067 / 1809	10%	0.30	46 / 472
uterus	5%	2.52	9 / 170	49%	2.89	223 / 459
adipose	46%	27.39	548 / 1204	0%	0	0 / 0
blood vessel	26%	12.37	341 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	11%	0.38	9 / 80
liver	0%	0.28	1 / 226	10%	0.50	39 / 406
spleen	5%	1.33	11 / 241	0%	0	0 / 0
heart	2%	0.77	17 / 861	0%	0	0 / 0
muscle	1%	0.33	5 / 803	0%	0	0 / 0
peripheral blood	0%	0.02	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030719	Biological process	P granule organization
GO_0007283	Biological process	spermatogenesis
GO_0007286	Biological process	spermatid development
GO_0141007	Biological process	siRNA-mediated retrotransposon silencing by heterochromatin formation
GO_0034587	Biological process	piRNA processing
GO_0071546	Cellular component	pi-body
GO_0033391	Cellular component	chromatoid body
GO_0045202	Cellular component	synapse
GO_0043186	Cellular component	P granule

Gene name	TDRD5
Protein name	Tudor domain containing 5 Tudor domain-containing protein 5
Synonyms	hCG_2024910 TUDOR3
Description	FUNCTION: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). . FUNCTION: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly. .
Accessions	ENST00000444136.6 [Q8NAT2-1] Q8NAT2 ENST00000367614.5 [Q8NAT2-3] ENST00000417329.1 A0A0C4DG74 ENST00000294848.12 [Q8NAT2-3] A0A024R910

TDRD5 report