Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| duct epithelial cell | 5 studies | 58% ± 22% | |
| basal cell | 5 studies | 20% ± 3% | |
| secretory cell | 3 studies | 19% ± 0% | |
| mucus secreting cell | 3 studies | 65% ± 31% | |
| respiratory goblet cell | 3 studies | 16% ± 1% |
Insufficient scRNA-seq data for expression of TCN1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 44% | 259.92 | 145 / 328 | 89% | 407.56 | 158 / 178 |
| stomach | 74% | 2363.13 | 265 / 359 | 50% | 60.12 | 143 / 286 |
| esophagus | 38% | 576.13 | 555 / 1445 | 50% | 35.28 | 92 / 183 |
| breast | 49% | 438.67 | 227 / 459 | 34% | 72.31 | 378 / 1118 |
| peripheral blood | 81% | 1985.09 | 754 / 929 | 0% | 0 | 0 / 0 |
| spleen | 74% | 327.03 | 178 / 241 | 0% | 0 | 0 / 0 |
| lung | 34% | 88.05 | 197 / 578 | 36% | 42.68 | 415 / 1155 |
| skin | 11% | 26.78 | 193 / 1809 | 43% | 79.64 | 201 / 472 |
| intestine | 2% | 10.55 | 24 / 966 | 50% | 80.92 | 266 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 49% | 33.03 | 22 / 45 |
| uterus | 8% | 34.82 | 13 / 170 | 41% | 42.54 | 188 / 459 |
| bladder | 0% | 0 | 0 / 21 | 40% | 57.00 | 204 / 504 |
| prostate | 29% | 92.83 | 70 / 245 | 6% | 1.76 | 32 / 502 |
| liver | 7% | 9.94 | 15 / 226 | 5% | 3.25 | 21 / 406 |
| kidney | 3% | 4.07 | 3 / 89 | 4% | 6.71 | 39 / 901 |
| thymus | 1% | 2.69 | 6 / 653 | 3% | 3.63 | 21 / 605 |
| eye | 0% | 0 | 0 / 0 | 4% | 1.28 | 3 / 80 |
| adrenal gland | 0% | 22.19 | 1 / 258 | 2% | 7.86 | 5 / 230 |
| ovary | 0% | 0 | 0 / 180 | 2% | 1.36 | 9 / 430 |
| adipose | 2% | 2.77 | 23 / 1204 | 0% | 0 | 0 / 0 |
| heart | 1% | 1.34 | 10 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 3.80 | 4 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.25 | 5 / 2642 | 0% | 0.01 | 1 / 705 |
| blood vessel | 0% | 0.25 | 3 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006824 | Biological process | cobalt ion transport |
| GO_0015889 | Biological process | cobalamin transport |
| GO_0005615 | Cellular component | extracellular space |
| GO_1904724 | Cellular component | tertiary granule lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0031419 | Molecular function | cobalamin binding |
| GO_0140313 | Molecular function | molecular sequestering activity |
| GO_0140355 | Molecular function | cargo receptor ligand activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TCN1 |
| Protein name | Transcobalamin-1 (TC-1) (Haptocorrin) (HC) (Protein R) (Transcobalamin I) (TC I) (TCI) |
| Synonyms | TC1 |
| Description | FUNCTION: Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach. |
| Accessions | ENST00000257264.4 P20061 |