I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 27% ± 8% | |
| abnormal cell | 3 studies | 16% ± 1% | |
| astrocyte | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 27% ± 8% | |
| abnormal cell | 3 studies | 16% ± 1% | |
| astrocyte | 3 studies | 18% ± 3% |
Insufficient scRNA-seq data for expression of TBC1D17 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 5180.97 | 258 / 258 | 100% | 46.22 | 230 / 230 |
| esophagus | 100% | 4817.79 | 1445 / 1445 | 100% | 28.37 | 183 / 183 |
| liver | 100% | 3522.74 | 226 / 226 | 100% | 29.61 | 406 / 406 |
| ovary | 100% | 6489.61 | 180 / 180 | 100% | 44.50 | 430 / 430 |
| thymus | 100% | 6496.85 | 653 / 653 | 100% | 47.86 | 605 / 605 |
| brain | 100% | 4760.61 | 2639 / 2642 | 100% | 51.75 | 705 / 705 |
| uterus | 100% | 6567.98 | 170 / 170 | 100% | 33.61 | 458 / 459 |
| skin | 100% | 5319.13 | 1806 / 1809 | 100% | 34.80 | 471 / 472 |
| prostate | 100% | 5905.15 | 245 / 245 | 100% | 44.56 | 500 / 502 |
| intestine | 100% | 4985.46 | 966 / 966 | 99% | 24.53 | 524 / 527 |
| kidney | 100% | 3999.84 | 89 / 89 | 99% | 31.57 | 895 / 901 |
| stomach | 100% | 3953.36 | 359 / 359 | 99% | 25.79 | 284 / 286 |
| pancreas | 100% | 3323.70 | 327 / 328 | 99% | 31.29 | 177 / 178 |
| breast | 100% | 5335.91 | 459 / 459 | 99% | 34.34 | 1107 / 1118 |
| lung | 100% | 4271.63 | 576 / 578 | 99% | 28.94 | 1144 / 1155 |
| bladder | 100% | 5516.86 | 21 / 21 | 98% | 29.26 | 495 / 504 |
| adipose | 100% | 4826.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 5307.80 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 54.16 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 35.54 | 29 / 29 |
| muscle | 100% | 8461.96 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4785.82 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 31.19 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 26.25 | 1 / 1 |
| heart | 98% | 3219.45 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2489.93 | 911 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
| GO_0015031 | Biological process | protein transport |
| GO_0006914 | Biological process | autophagy |
| GO_1902017 | Biological process | regulation of cilium assembly |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0055037 | Cellular component | recycling endosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005776 | Cellular component | autophagosome |
| GO_0005515 | Molecular function | protein binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| Gene name | TBC1D17 |
| Protein name | TBC1 domain family member 17 |
| Synonyms | |
| Description | FUNCTION: Probable RAB GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR) . Involved in regulation of autophagy. . |
| Accessions | Q9HA65 ENST00000599049.6 ENST00000594984.1 ENST00000594996.5 M0R2L2 M0QXA2 ENST00000221543.10 [Q9HA65-1] ENST00000535102.6 [Q9HA65-2] M0QYC9 |
