TARS2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	3 studies	20% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TARS2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1355.67	1445 / 1445	100%	25.99	183 / 183
liver	100%	1752.00	226 / 226	100%	35.61	406 / 406
ovary	100%	1468.86	180 / 180	100%	34.17	430 / 430
skin	100%	1707.91	1809 / 1809	100%	47.30	472 / 472
breast	100%	1457.04	459 / 459	100%	50.05	1117 / 1118
thymus	100%	1481.44	653 / 653	100%	27.62	604 / 605
uterus	100%	1358.47	170 / 170	100%	39.39	458 / 459
brain	100%	1518.86	2636 / 2642	100%	34.63	705 / 705
stomach	100%	1214.65	359 / 359	100%	28.92	285 / 286
prostate	100%	1325.92	245 / 245	100%	26.84	500 / 502
kidney	100%	1297.09	89 / 89	100%	27.40	897 / 901
bladder	100%	1393.00	21 / 21	99%	35.50	501 / 504
intestine	100%	1268.93	965 / 966	99%	29.87	524 / 527
lung	99%	1085.25	572 / 578	100%	32.90	1155 / 1155
adrenal gland	100%	2361.23	258 / 258	99%	22.07	227 / 230
pancreas	99%	820.05	325 / 328	99%	26.26	176 / 178
adipose	100%	1294.10	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	30.58	80 / 80
lymph node	0%	0	0 / 0	100%	49.86	29 / 29
muscle	100%	2234.60	803 / 803	0%	0	0 / 0
spleen	100%	1941.43	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	31.95	45 / 45
ureter	0%	0	0 / 0	100%	13.81	1 / 1
blood vessel	100%	972.81	1332 / 1335	0%	0	0 / 0
heart	99%	1503.35	849 / 861	0%	0	0 / 0
peripheral blood	88%	1263.10	821 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0106074	Biological process	aminoacyl-tRNA metabolism involved in translational fidelity
GO_0006435	Biological process	threonyl-tRNA aminoacylation
GO_0070159	Biological process	mitochondrial threonyl-tRNA aminoacylation
GO_0005575	Cellular component	cellular_component
GO_0005759	Cellular component	mitochondrial matrix
GO_0042803	Molecular function	protein homodimerization activity
GO_0002161	Molecular function	aminoacyl-tRNA editing activity
GO_0004829	Molecular function	threonine-tRNA ligase activity
GO_0005515	Molecular function	protein binding
GO_0005524	Molecular function	ATP binding

Gene name	TARS2
Protein name	Threonyl-tRNA synthetase 2, mitochondrial threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase) Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like 1) Threonyl-tRNA synthetase 2
Synonyms	TARSL1
Description	FUNCTION: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain. .
Accessions	U3KQG0 Q5T5E9 ENST00000369064.8 [Q9BW92-1] ENST00000369051.7 U3KQ50 Q9BW92 ENST00000467982.6 ENST00000606933.5 A0A810V332 A0A810V1V9 ENST00000369054.6 [Q9BW92-2]

TARS2 report